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Can Frailty Be a Predictor of ICD Shock after the Implantation of a Cardioverter Defibrillator in Elderly Patients?

Introduction: The aim of the study was to assess the prevalence of frailty among elderly patients who had an implanted cardioverter defibrillator, as well as the influence of frailty on the main endpoints during the follow-up. Methods: The study included 103 patients > 60 years of age (85M, aged...

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Autores principales: Mlynarska, Agnieszka, Mlynarski, Rafal, Uchmanowicz, Bartosz, Mikuľáková, Wioletta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470717/
https://www.ncbi.nlm.nih.gov/pubmed/34577506
http://dx.doi.org/10.3390/s21186299
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author Mlynarska, Agnieszka
Mlynarski, Rafal
Uchmanowicz, Bartosz
Mikuľáková, Wioletta
author_facet Mlynarska, Agnieszka
Mlynarski, Rafal
Uchmanowicz, Bartosz
Mikuľáková, Wioletta
author_sort Mlynarska, Agnieszka
collection PubMed
description Introduction: The aim of the study was to assess the prevalence of frailty among elderly patients who had an implanted cardioverter defibrillator, as well as the influence of frailty on the main endpoints during the follow-up. Methods: The study included 103 patients > 60 years of age (85M, aged 71.56–8.17 years). All of the patients had an implanted single or dual-chamber cardioverter-defibrillator. In the research, there was a 12-month follow-up. The occurrence of frailty syndrome was assessed using the Tilburg Frailty Indicator scale (TFI). Results: Frailty syndrome was diagnosed in 75.73% of the patients that were included in the study. The mean values of the TFI were 6.55 ± 2.67, in the physical domain 4.06 ± 1.79, in the psychological domain 2.06 ± 1.10, and in the social domain 0.44 ± 0.55. During the follow-up period, 27.2% of patients had a defibrillator cardioverter electric shock, which occurred statistically more often in patients with diagnosed frailty syndrome (34.6%) compared to the robust patients (4%); p = 0.0062. In the logistic regression, frailty (OR: 1.203, 95% CI:1.0126–1.4298; p < 0.030) was an independent predictor of a defibrillator cardioverter electric shock. Similarly, in the logistic regression, frailty (OR: 1.3623, 95% CI:1.0290–1.8035; p = 0.019) was also an independent predictor for inadequate electric shocks. Conclusion: About three-quarters of the elderly patients that had qualified for ICD implantation were affected by frailty syndrome. In the frailty subgroup, adequate and inadequate shocks occurred more often compared to the robust patients.
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spelling pubmed-84707172021-09-27 Can Frailty Be a Predictor of ICD Shock after the Implantation of a Cardioverter Defibrillator in Elderly Patients? Mlynarska, Agnieszka Mlynarski, Rafal Uchmanowicz, Bartosz Mikuľáková, Wioletta Sensors (Basel) Communication Introduction: The aim of the study was to assess the prevalence of frailty among elderly patients who had an implanted cardioverter defibrillator, as well as the influence of frailty on the main endpoints during the follow-up. Methods: The study included 103 patients > 60 years of age (85M, aged 71.56–8.17 years). All of the patients had an implanted single or dual-chamber cardioverter-defibrillator. In the research, there was a 12-month follow-up. The occurrence of frailty syndrome was assessed using the Tilburg Frailty Indicator scale (TFI). Results: Frailty syndrome was diagnosed in 75.73% of the patients that were included in the study. The mean values of the TFI were 6.55 ± 2.67, in the physical domain 4.06 ± 1.79, in the psychological domain 2.06 ± 1.10, and in the social domain 0.44 ± 0.55. During the follow-up period, 27.2% of patients had a defibrillator cardioverter electric shock, which occurred statistically more often in patients with diagnosed frailty syndrome (34.6%) compared to the robust patients (4%); p = 0.0062. In the logistic regression, frailty (OR: 1.203, 95% CI:1.0126–1.4298; p < 0.030) was an independent predictor of a defibrillator cardioverter electric shock. Similarly, in the logistic regression, frailty (OR: 1.3623, 95% CI:1.0290–1.8035; p = 0.019) was also an independent predictor for inadequate electric shocks. Conclusion: About three-quarters of the elderly patients that had qualified for ICD implantation were affected by frailty syndrome. In the frailty subgroup, adequate and inadequate shocks occurred more often compared to the robust patients. MDPI 2021-09-20 /pmc/articles/PMC8470717/ /pubmed/34577506 http://dx.doi.org/10.3390/s21186299 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Mlynarska, Agnieszka
Mlynarski, Rafal
Uchmanowicz, Bartosz
Mikuľáková, Wioletta
Can Frailty Be a Predictor of ICD Shock after the Implantation of a Cardioverter Defibrillator in Elderly Patients?
title Can Frailty Be a Predictor of ICD Shock after the Implantation of a Cardioverter Defibrillator in Elderly Patients?
title_full Can Frailty Be a Predictor of ICD Shock after the Implantation of a Cardioverter Defibrillator in Elderly Patients?
title_fullStr Can Frailty Be a Predictor of ICD Shock after the Implantation of a Cardioverter Defibrillator in Elderly Patients?
title_full_unstemmed Can Frailty Be a Predictor of ICD Shock after the Implantation of a Cardioverter Defibrillator in Elderly Patients?
title_short Can Frailty Be a Predictor of ICD Shock after the Implantation of a Cardioverter Defibrillator in Elderly Patients?
title_sort can frailty be a predictor of icd shock after the implantation of a cardioverter defibrillator in elderly patients?
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470717/
https://www.ncbi.nlm.nih.gov/pubmed/34577506
http://dx.doi.org/10.3390/s21186299
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