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Study on Data Partition for Delimitation of Masses in Mammography

Mammography is the primary medical imaging method used for routine screening and early detection of breast cancer in women. However, the process of manually inspecting, detecting, and delimiting the tumoral massess in 2D images is a very time-consuming task, subject to human errors due to fatigue. T...

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Detalles Bibliográficos
Autores principales: Viegas, Luís, Domingues, Inês, Mendes, Mateus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470756/
https://www.ncbi.nlm.nih.gov/pubmed/34564100
http://dx.doi.org/10.3390/jimaging7090174
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author Viegas, Luís
Domingues, Inês
Mendes, Mateus
author_facet Viegas, Luís
Domingues, Inês
Mendes, Mateus
author_sort Viegas, Luís
collection PubMed
description Mammography is the primary medical imaging method used for routine screening and early detection of breast cancer in women. However, the process of manually inspecting, detecting, and delimiting the tumoral massess in 2D images is a very time-consuming task, subject to human errors due to fatigue. Therefore, integrated computer-aided detection systems have been proposed, based on modern computer vision and machine learning methods. In the present work, mammogram images from the publicly available Inbreast dataset are first converted to pseudo-color and then used to train and test a Mask R-CNN deep neural network. The most common approach is to start with a dataset and split the images into train and test set randomly. However, since there are often two or more images of the same case in the dataset, the way the dataset is split may have an impact on the results. Our experiments show that random partition of the data can produce unreliable training, so the dataset must be split using case-wise partition for more stable results. In experimental results, the method achieves an average true positive rate of 0.936 with 0.063 standard deviation using random partition and 0.908 with 0.002 standard deviation using case-wise partition, showing that case-wise partition must be used for more reliable results.
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spelling pubmed-84707562021-10-28 Study on Data Partition for Delimitation of Masses in Mammography Viegas, Luís Domingues, Inês Mendes, Mateus J Imaging Article Mammography is the primary medical imaging method used for routine screening and early detection of breast cancer in women. However, the process of manually inspecting, detecting, and delimiting the tumoral massess in 2D images is a very time-consuming task, subject to human errors due to fatigue. Therefore, integrated computer-aided detection systems have been proposed, based on modern computer vision and machine learning methods. In the present work, mammogram images from the publicly available Inbreast dataset are first converted to pseudo-color and then used to train and test a Mask R-CNN deep neural network. The most common approach is to start with a dataset and split the images into train and test set randomly. However, since there are often two or more images of the same case in the dataset, the way the dataset is split may have an impact on the results. Our experiments show that random partition of the data can produce unreliable training, so the dataset must be split using case-wise partition for more stable results. In experimental results, the method achieves an average true positive rate of 0.936 with 0.063 standard deviation using random partition and 0.908 with 0.002 standard deviation using case-wise partition, showing that case-wise partition must be used for more reliable results. MDPI 2021-09-02 /pmc/articles/PMC8470756/ /pubmed/34564100 http://dx.doi.org/10.3390/jimaging7090174 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Viegas, Luís
Domingues, Inês
Mendes, Mateus
Study on Data Partition for Delimitation of Masses in Mammography
title Study on Data Partition for Delimitation of Masses in Mammography
title_full Study on Data Partition for Delimitation of Masses in Mammography
title_fullStr Study on Data Partition for Delimitation of Masses in Mammography
title_full_unstemmed Study on Data Partition for Delimitation of Masses in Mammography
title_short Study on Data Partition for Delimitation of Masses in Mammography
title_sort study on data partition for delimitation of masses in mammography
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470756/
https://www.ncbi.nlm.nih.gov/pubmed/34564100
http://dx.doi.org/10.3390/jimaging7090174
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