MiR-137 Targets the 3′ Untranslated Region of MSH2: Potential Implications in Lynch Syndrome-Related Colorectal Cancer

SIMPLE SUMMARY: In a previous study, we identified a patient carrying the variant c.*226A>G in the MSH2 3′ untranslated region that showed overexpression of MSH2 protein. In this study, we hypothesized that the MSH2 3′UTR contained a seed region for miR-137, indicating MSH2 was indeed targeted by...

Descripción completa

Detalles Bibliográficos
Autores principales: Liccardo, Raffaella, Sessa, Raffaele, Trombetti, Silvia, De Rosa, Marina, Izzo, Paola, Grosso, Michela, Duraturo, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470766/
https://www.ncbi.nlm.nih.gov/pubmed/34572889
http://dx.doi.org/10.3390/cancers13184662

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470766/
https://www.ncbi.nlm.nih.gov/pubmed/34572889
http://dx.doi.org/10.3390/cancers13184662

Ejemplares similares