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Adipose-Derived Extract Suppresses IL-1β-Induced Inflammatory Signaling Pathways in Human Chondrocytes and Ameliorates the Cartilage Destruction of Experimental Osteoarthritis in Rats

We investigated the effects of adipose-derived extract (AE) on cultured chondrocytes and in vivo cartilage destruction. AE was prepared from human adipose tissues using a nonenzymatic approach. Cultured human chondrocytes were stimulated with interleukin-1 beta (IL-1β) with or without different conc...

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Detalles Bibliográficos
Autores principales:	Ohashi, Hideki, Nishida, Keiichiro, Yoshida, Aki, Nasu, Yoshihisa, Nakahara, Ryuichi, Matsumoto, Yoshinori, Takeshita, Ayumu, Kaneda, Daisuke, Saeki, Masanori, Ozaki, Toshifumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470808/ https://www.ncbi.nlm.nih.gov/pubmed/34575945 http://dx.doi.org/10.3390/ijms22189781

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