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Clinical Efficacy of Novel Patient-Covering Negative-Pressure Box for Shielding Virus Transmission during Esophagogastroduodenoscopy: A Prospective Observational Study

Esophagogastroduodenoscopy (EGD) has a high risk of virus transmission during the current coronavirus disease 2019 era, and preventive measures are under investigation. We investigated the effectiveness of a newly developed patient-covering negative-pressure box system (Endo barrier(®)) (EB) for EGD...

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Autores principales: Fujihara, Shintaro, Kobara, Hideki, Nishiyama, Noriko, Tada, Naoya, Kozuka, Kazuhiro, Matsui, Takanori, Chiyo, Taiga, Kobayashi, Nobuya, Shi, Tingting, Yachida, Tatsuo, Uchida, Toshio, Nagatomi, Taichi, Oba, Haruo, Masaki, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470820/
https://www.ncbi.nlm.nih.gov/pubmed/34574020
http://dx.doi.org/10.3390/diagnostics11091679
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author Fujihara, Shintaro
Kobara, Hideki
Nishiyama, Noriko
Tada, Naoya
Kozuka, Kazuhiro
Matsui, Takanori
Chiyo, Taiga
Kobayashi, Nobuya
Shi, Tingting
Yachida, Tatsuo
Uchida, Toshio
Nagatomi, Taichi
Oba, Haruo
Masaki, Tsutomu
author_facet Fujihara, Shintaro
Kobara, Hideki
Nishiyama, Noriko
Tada, Naoya
Kozuka, Kazuhiro
Matsui, Takanori
Chiyo, Taiga
Kobayashi, Nobuya
Shi, Tingting
Yachida, Tatsuo
Uchida, Toshio
Nagatomi, Taichi
Oba, Haruo
Masaki, Tsutomu
author_sort Fujihara, Shintaro
collection PubMed
description Esophagogastroduodenoscopy (EGD) has a high risk of virus transmission during the current coronavirus disease 2019 era, and preventive measures are under investigation. We investigated the effectiveness of a newly developed patient-covering negative-pressure box system (Endo barrier(®)) (EB) for EGD. Eighty consecutive unsedated patients who underwent screening EGD with EB use were prospectively enrolled. To examine the aerosol ratio before, during, and after EGD, 0.3- and 0.5-μm aerosols were measured every 60 s using an optical counter. Moreover, the degree of contamination of the examiners’ goggles and vinyl gowns was assessed before and after EGD using a rapid adenosine triphosphate (ATP) test for simulated droplets. Data were available in 73 patients and showed that 0.3- and 0.5-μm particles did not increase in 95.8% (70/73) and 94.5% (69/73) of patients during EGD under EB. There were no significant differences in the total 0.3- or 0.5-μm particle counts before versus after EGD. The difference in the ATP levels before and after EGD was −0.6 ± 16.6 relative light units (RLU) on goggles and 1.59 ± 19.9 RLU on gowns (both within the cutoff value). EB use during EGD may provide a certain preventive effect against aerosols and droplets, decreasing examiners’ exposure to viruses.
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spelling pubmed-84708202021-09-27 Clinical Efficacy of Novel Patient-Covering Negative-Pressure Box for Shielding Virus Transmission during Esophagogastroduodenoscopy: A Prospective Observational Study Fujihara, Shintaro Kobara, Hideki Nishiyama, Noriko Tada, Naoya Kozuka, Kazuhiro Matsui, Takanori Chiyo, Taiga Kobayashi, Nobuya Shi, Tingting Yachida, Tatsuo Uchida, Toshio Nagatomi, Taichi Oba, Haruo Masaki, Tsutomu Diagnostics (Basel) Article Esophagogastroduodenoscopy (EGD) has a high risk of virus transmission during the current coronavirus disease 2019 era, and preventive measures are under investigation. We investigated the effectiveness of a newly developed patient-covering negative-pressure box system (Endo barrier(®)) (EB) for EGD. Eighty consecutive unsedated patients who underwent screening EGD with EB use were prospectively enrolled. To examine the aerosol ratio before, during, and after EGD, 0.3- and 0.5-μm aerosols were measured every 60 s using an optical counter. Moreover, the degree of contamination of the examiners’ goggles and vinyl gowns was assessed before and after EGD using a rapid adenosine triphosphate (ATP) test for simulated droplets. Data were available in 73 patients and showed that 0.3- and 0.5-μm particles did not increase in 95.8% (70/73) and 94.5% (69/73) of patients during EGD under EB. There were no significant differences in the total 0.3- or 0.5-μm particle counts before versus after EGD. The difference in the ATP levels before and after EGD was −0.6 ± 16.6 relative light units (RLU) on goggles and 1.59 ± 19.9 RLU on gowns (both within the cutoff value). EB use during EGD may provide a certain preventive effect against aerosols and droplets, decreasing examiners’ exposure to viruses. MDPI 2021-09-14 /pmc/articles/PMC8470820/ /pubmed/34574020 http://dx.doi.org/10.3390/diagnostics11091679 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Fujihara, Shintaro
Kobara, Hideki
Nishiyama, Noriko
Tada, Naoya
Kozuka, Kazuhiro
Matsui, Takanori
Chiyo, Taiga
Kobayashi, Nobuya
Shi, Tingting
Yachida, Tatsuo
Uchida, Toshio
Nagatomi, Taichi
Oba, Haruo
Masaki, Tsutomu
Clinical Efficacy of Novel Patient-Covering Negative-Pressure Box for Shielding Virus Transmission during Esophagogastroduodenoscopy: A Prospective Observational Study
title Clinical Efficacy of Novel Patient-Covering Negative-Pressure Box for Shielding Virus Transmission during Esophagogastroduodenoscopy: A Prospective Observational Study
title_full Clinical Efficacy of Novel Patient-Covering Negative-Pressure Box for Shielding Virus Transmission during Esophagogastroduodenoscopy: A Prospective Observational Study
title_fullStr Clinical Efficacy of Novel Patient-Covering Negative-Pressure Box for Shielding Virus Transmission during Esophagogastroduodenoscopy: A Prospective Observational Study
title_full_unstemmed Clinical Efficacy of Novel Patient-Covering Negative-Pressure Box for Shielding Virus Transmission during Esophagogastroduodenoscopy: A Prospective Observational Study
title_short Clinical Efficacy of Novel Patient-Covering Negative-Pressure Box for Shielding Virus Transmission during Esophagogastroduodenoscopy: A Prospective Observational Study
title_sort clinical efficacy of novel patient-covering negative-pressure box for shielding virus transmission during esophagogastroduodenoscopy: a prospective observational study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470820/
https://www.ncbi.nlm.nih.gov/pubmed/34574020
http://dx.doi.org/10.3390/diagnostics11091679
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