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Histologic Transformation in EGFR-Mutant Lung Adenocarcinomas: Mechanisms and Therapeutic Implications

SIMPLE SUMMARY: Despite being effective initially, almost all patients eventually develop resistance to EGFR-tyrosine kinase inhibitors (TKI). Changes in the histology of the tumor have been increasingly recognized as a critical mechanism of resistance to EGFR-directed therapies. This article summar...

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Detalles Bibliográficos
Autores principales:	Pathak, Ranjan, Villaflor, Victoria M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470834/ https://www.ncbi.nlm.nih.gov/pubmed/34572868 http://dx.doi.org/10.3390/cancers13184641

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