Cargando…

Next-Generation Genome-Scale Metabolic Modeling through Integration of Regulatory Mechanisms

Genome-scale metabolic models (GEMs) are powerful tools for understanding metabolism from a systems-level perspective. However, GEMs in their most basic form fail to account for cellular regulation. A diverse set of mechanisms regulate cellular metabolism, enabling organisms to respond to a wide ran...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chung, Carolina H., Lin, Da-Wei, Eames, Alec, Chandrasekaran, Sriram
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470976/ https://www.ncbi.nlm.nih.gov/pubmed/34564422 http://dx.doi.org/10.3390/metabo11090606

Ejemplares similares

Metabolic Constraint-Based Refinement of Transcriptional Regulatory Networks
por: Chandrasekaran, Sriram, et al.
Publicado: (2013)

Genome-scale network model of metabolism and histone acetylation reveals metabolic dependencies of histone deacetylase inhibitors
por: Shen, Fangzhou, et al.
Publicado: (2019)

A flux-based machine learning model to simulate the impact of pathogen metabolic heterogeneity on drug interactions
por: Chung, Carolina H, et al.
Publicado: (2022)

Data-driven integration of genome-scale regulatory and metabolic network models
por: Imam, Saheed, et al.
Publicado: (2015)

Genomics through the lens of next-generation sequencing
por: Capra, John A, et al.
Publicado: (2010)

Integrative analysis of clinical health records, imaging and pathogen genomics identifies personalized predictors of disease prognosis in tuberculosis
por: Sambarey, Awanti, et al.
Publicado: (2022)

An integrated pipeline for next-generation sequencing and annotation of mitochondrial genomes
por: Jex, Aaron R., et al.
Publicado: (2010)

inGAP: an integrated next-generation genome analysis pipeline
por: Qi, Ji, et al.
Publicado: (2010)

Perspectives of Integrative Cancer Genomics in Next Generation Sequencing Era
por: Kwon, So Mee, et al.
Publicado: (2012)

Next‐generation biological control: the need for integrating genetics and genomics
por: Leung, Kelley, et al.
Publicado: (2020)

CIPHER: a flexible and extensive workflow platform for integrative next-generation sequencing data analysis and genomic regulatory element prediction
por: Guzman, Carlos, et al.
Publicado: (2017)

TIGER: Toolbox for integrating genome-scale metabolic models, expression data, and transcriptional regulatory networks
por: Jensen, Paul A, et al.
Publicado: (2011)

In the hunt for genomic markers of metabolic resistance to pyrethroids in the mosquito Aedes aegypti: An integrated next-generation sequencing approach
por: Faucon, Frederic, et al.
Publicado: (2017)

Large-scale integrated super-computing platform for next generation virtual drug discovery
por: Mitchell, Wayne, et al.
Publicado: (2011)

Inferring population structure in biobank-scale genomic data
por: Chiu, Alec M., et al.
Publicado: (2022)

An Integrated Approach to Reconstructing Genome-Scale Transcriptional Regulatory Networks
por: Imam, Saheed, et al.
Publicado: (2015)

Next-generation cancer genomics
por: Mardis, Elaine R
Publicado: (2010)

Next-generation pathogen genomics
por: Weinstock, George M, et al.
Publicado: (2014)

Tying Metabolic Branches With Histone Tails Using Systems Biology
por: Chandrasekaran, Sriram
Publicado: (2019)

Dynamic genome-scale cell-specific metabolic models reveal novel inter-cellular and intra-cellular metabolic communications during ovarian follicle development
por: Peñalver Bernabé, Beatriz, et al.
Publicado: (2019)

Mutation Detection with Next-Generation Resequencing through a Mediator Genome
por: Wurtzel, Omri, et al.
Publicado: (2010)

Integration of omics data to generate and analyse COVID-19 specific genome-scale metabolic models
por: Režen, Tadeja, et al.
Publicado: (2022)

Next generation transcriptomes for next generation genomes using est2assembly
por: Papanicolaou, Alexie, et al.
Publicado: (2009)

Dissecting Murine Muscle Stem Cell Aging through Regeneration Using Integrative Genomic Analysis
por: Shcherbina, Anna, et al.
Publicado: (2020)

1248. Genomic Sequencing and Clinical Data Integration for Next-Generation Infection Prevention
por: Chen, Donald, et al.
Publicado: (2018)

ChromDL: A Next-Generation Regulatory DNA Classifier
por: Hill, Christopher, et al.
Publicado: (2023)

Integrative Analysis of Next-Generation Sequencing for Next-Generation Cancer Research toward Artificial Intelligence
por: Park, Youngjun, et al.
Publicado: (2021)

Advanced technologies for next generation integrated circuits
por: Srivastava, Ashok, et al.
Publicado: (2020)

Next-Generation Biowarfare: Small in Scale, Sensational in Nature?
por: Gisselsson, David
Publicado: (2022)

Next-generation sequencing profiling of mitochondrial genomes in gout
por: Tseng, Chia-Chun, et al.
Publicado: (2018)

A system-level model for the microbial regulatory genome
por: Brooks, Aaron N, et al.
Publicado: (2014)

Uncovering disease mechanisms through network biology in the era of Next Generation Sequencing
por: Piñero, Janet, et al.
Publicado: (2016)

Integration of metabolic databases for the reconstruction of genome-scale metabolic networks
por: Radrich, Karin, et al.
Publicado: (2010)

VirusFinder: Software for Efficient and Accurate Detection of Viruses and Their Integration Sites in Host Genomes through Next Generation Sequencing Data
por: Wang, Qingguo, et al.
Publicado: (2013)

Application of targeted enrichment to next-generation sequencing of retroviruses integrated into the host human genome
por: Miyazato, Paola, et al.
Publicado: (2016)

Metabolic Myopathies in the Era of Next-Generation Sequencing
por: Urtizberea, Jon Andoni, et al.
Publicado: (2023)

BAMscale: quantification of next-generation sequencing peaks and generation of scaled coverage tracks
por: Pongor, Lorinc S., et al.
Publicado: (2020)

Integrating plant molecular farming and materials research for next-generation vaccines
por: Chung, Young Hun, et al.
Publicado: (2021)

Mechanism for DNA transposons to generate introns on genomic scales
por: Huff, Jason T., et al.
Publicado: (2016)

Integrating Global Citizen Science Platforms to Enable Next-Generation Surveillance of Invasive and Vector Mosquitoes
por: Carney, Ryan M., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_i36onsg9qp2pbs0sku3d34mkn2