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Fabrication of pH/Reduction Sensitive Polyethylene Glycol-Based Micelles for Enhanced Intracellular Drug Release

At present, the drug is still difficult to release completely and quickly only with single stimulation. In order to promote the rapid release of polymeric micelles at tumor site, pH/reduction sensitive polymers (PCT) containing disulfide bonds and orthoester groups were synthesized. The PCT polymers...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Yang, Fuwei, Shan, Xiaotian, Xu, Jiamin, Fang, Wenjie, Zhou, Juan, Qiu, Lipeng, Chen, Jinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470983/
https://www.ncbi.nlm.nih.gov/pubmed/34575539
http://dx.doi.org/10.3390/pharmaceutics13091464