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Does the Combined Effect of Resistance Training with EPO and Iron Sulfate Improve Iron Metabolism in Older Individuals with End-Stage Renal Disease?

We sought to investigate the effects of resistance training (RT) combined with erythropoietin (EPO) and iron sulfate on the hemoglobin, hepcidin, ferritin, iron status, and inflammatory profile in older individuals with end-stage renal disease (ESRD). ESRD patients (n: 157; age: 66.8 ± 3.6; body mas...

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Autores principales: Corrêa, Hugo de Luca, Alfaro-Magallanes, Víctor Manuel, Moura, Sting Ray Gouveia, Neves, Rodrigo Vanerson Passos, Deus, Lysleine Alves, Honorato, Fernando Sousa, Silva, Victor Lopes, Raab, Artur Temizio Oppelt, Maia, Beatriz Carneiro Habbema, Padula, Isabela Akaishi, de Gusmão Alves, Lucas Santos, Machado, Rafaela Araújo, Reis, Andrea Lucena, Prestes, Jonato, Ferreira, Carlos Ernesto Santos, Neto, Luiz Sinésio da Silva, Tavares, Fernanda Silveira, Andrade, Rosângela Vieira, Rosa, Thiago dos Santos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471184/
https://www.ncbi.nlm.nih.gov/pubmed/34579127
http://dx.doi.org/10.3390/nu13093250
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author Corrêa, Hugo de Luca
Alfaro-Magallanes, Víctor Manuel
Moura, Sting Ray Gouveia
Neves, Rodrigo Vanerson Passos
Deus, Lysleine Alves
Honorato, Fernando Sousa
Silva, Victor Lopes
Raab, Artur Temizio Oppelt
Maia, Beatriz Carneiro Habbema
Padula, Isabela Akaishi
de Gusmão Alves, Lucas Santos
Machado, Rafaela Araújo
Reis, Andrea Lucena
Prestes, Jonato
Ferreira, Carlos Ernesto Santos
Neto, Luiz Sinésio da Silva
Tavares, Fernanda Silveira
Andrade, Rosângela Vieira
Rosa, Thiago dos Santos
author_facet Corrêa, Hugo de Luca
Alfaro-Magallanes, Víctor Manuel
Moura, Sting Ray Gouveia
Neves, Rodrigo Vanerson Passos
Deus, Lysleine Alves
Honorato, Fernando Sousa
Silva, Victor Lopes
Raab, Artur Temizio Oppelt
Maia, Beatriz Carneiro Habbema
Padula, Isabela Akaishi
de Gusmão Alves, Lucas Santos
Machado, Rafaela Araújo
Reis, Andrea Lucena
Prestes, Jonato
Ferreira, Carlos Ernesto Santos
Neto, Luiz Sinésio da Silva
Tavares, Fernanda Silveira
Andrade, Rosângela Vieira
Rosa, Thiago dos Santos
author_sort Corrêa, Hugo de Luca
collection PubMed
description We sought to investigate the effects of resistance training (RT) combined with erythropoietin (EPO) and iron sulfate on the hemoglobin, hepcidin, ferritin, iron status, and inflammatory profile in older individuals with end-stage renal disease (ESRD). ESRD patients (n: 157; age: 66.8 ± 3.6; body mass: 73 ± 15; body mass index: 27 ± 3), were assigned to control (CTL; n: 76) and exercise groups (RT; n: 81). The CTL group was divided according to the iron treatment received: without iron treatment (CTL—none; n = 19), treated only with iron sulfate or EPO (CTL—EPO or IRON; n = 19), and treated with both iron sulfate and EPO (CTL—EPO + IRON; n = 76). The RT group followed the same pattern: (RT—none; n = 20), (RT—EPO or IRON; n = 18), and (RT—EPO + IRON; n = 86). RT consisted of 24 weeks/3 days per week at moderate intensity of full-body resistance exercises prior to the hemodialysis section. The RT group, regardless of the iron treatment, improved iron metabolism in older individuals with ESRD. These results provide some clues on the effects of RT and its combination with EPO and iron sulfate in this population, highlighting RT as an important coadjutant in ESRD-iron deficiency.
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spelling pubmed-84711842021-09-27 Does the Combined Effect of Resistance Training with EPO and Iron Sulfate Improve Iron Metabolism in Older Individuals with End-Stage Renal Disease? Corrêa, Hugo de Luca Alfaro-Magallanes, Víctor Manuel Moura, Sting Ray Gouveia Neves, Rodrigo Vanerson Passos Deus, Lysleine Alves Honorato, Fernando Sousa Silva, Victor Lopes Raab, Artur Temizio Oppelt Maia, Beatriz Carneiro Habbema Padula, Isabela Akaishi de Gusmão Alves, Lucas Santos Machado, Rafaela Araújo Reis, Andrea Lucena Prestes, Jonato Ferreira, Carlos Ernesto Santos Neto, Luiz Sinésio da Silva Tavares, Fernanda Silveira Andrade, Rosângela Vieira Rosa, Thiago dos Santos Nutrients Article We sought to investigate the effects of resistance training (RT) combined with erythropoietin (EPO) and iron sulfate on the hemoglobin, hepcidin, ferritin, iron status, and inflammatory profile in older individuals with end-stage renal disease (ESRD). ESRD patients (n: 157; age: 66.8 ± 3.6; body mass: 73 ± 15; body mass index: 27 ± 3), were assigned to control (CTL; n: 76) and exercise groups (RT; n: 81). The CTL group was divided according to the iron treatment received: without iron treatment (CTL—none; n = 19), treated only with iron sulfate or EPO (CTL—EPO or IRON; n = 19), and treated with both iron sulfate and EPO (CTL—EPO + IRON; n = 76). The RT group followed the same pattern: (RT—none; n = 20), (RT—EPO or IRON; n = 18), and (RT—EPO + IRON; n = 86). RT consisted of 24 weeks/3 days per week at moderate intensity of full-body resistance exercises prior to the hemodialysis section. The RT group, regardless of the iron treatment, improved iron metabolism in older individuals with ESRD. These results provide some clues on the effects of RT and its combination with EPO and iron sulfate in this population, highlighting RT as an important coadjutant in ESRD-iron deficiency. MDPI 2021-09-18 /pmc/articles/PMC8471184/ /pubmed/34579127 http://dx.doi.org/10.3390/nu13093250 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Corrêa, Hugo de Luca
Alfaro-Magallanes, Víctor Manuel
Moura, Sting Ray Gouveia
Neves, Rodrigo Vanerson Passos
Deus, Lysleine Alves
Honorato, Fernando Sousa
Silva, Victor Lopes
Raab, Artur Temizio Oppelt
Maia, Beatriz Carneiro Habbema
Padula, Isabela Akaishi
de Gusmão Alves, Lucas Santos
Machado, Rafaela Araújo
Reis, Andrea Lucena
Prestes, Jonato
Ferreira, Carlos Ernesto Santos
Neto, Luiz Sinésio da Silva
Tavares, Fernanda Silveira
Andrade, Rosângela Vieira
Rosa, Thiago dos Santos
Does the Combined Effect of Resistance Training with EPO and Iron Sulfate Improve Iron Metabolism in Older Individuals with End-Stage Renal Disease?
title Does the Combined Effect of Resistance Training with EPO and Iron Sulfate Improve Iron Metabolism in Older Individuals with End-Stage Renal Disease?
title_full Does the Combined Effect of Resistance Training with EPO and Iron Sulfate Improve Iron Metabolism in Older Individuals with End-Stage Renal Disease?
title_fullStr Does the Combined Effect of Resistance Training with EPO and Iron Sulfate Improve Iron Metabolism in Older Individuals with End-Stage Renal Disease?
title_full_unstemmed Does the Combined Effect of Resistance Training with EPO and Iron Sulfate Improve Iron Metabolism in Older Individuals with End-Stage Renal Disease?
title_short Does the Combined Effect of Resistance Training with EPO and Iron Sulfate Improve Iron Metabolism in Older Individuals with End-Stage Renal Disease?
title_sort does the combined effect of resistance training with epo and iron sulfate improve iron metabolism in older individuals with end-stage renal disease?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471184/
https://www.ncbi.nlm.nih.gov/pubmed/34579127
http://dx.doi.org/10.3390/nu13093250
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