Cargando…
Does the Combined Effect of Resistance Training with EPO and Iron Sulfate Improve Iron Metabolism in Older Individuals with End-Stage Renal Disease?
We sought to investigate the effects of resistance training (RT) combined with erythropoietin (EPO) and iron sulfate on the hemoglobin, hepcidin, ferritin, iron status, and inflammatory profile in older individuals with end-stage renal disease (ESRD). ESRD patients (n: 157; age: 66.8 ± 3.6; body mas...
Autores principales: | , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471184/ https://www.ncbi.nlm.nih.gov/pubmed/34579127 http://dx.doi.org/10.3390/nu13093250 |
_version_ | 1784574397706665984 |
---|---|
author | Corrêa, Hugo de Luca Alfaro-Magallanes, Víctor Manuel Moura, Sting Ray Gouveia Neves, Rodrigo Vanerson Passos Deus, Lysleine Alves Honorato, Fernando Sousa Silva, Victor Lopes Raab, Artur Temizio Oppelt Maia, Beatriz Carneiro Habbema Padula, Isabela Akaishi de Gusmão Alves, Lucas Santos Machado, Rafaela Araújo Reis, Andrea Lucena Prestes, Jonato Ferreira, Carlos Ernesto Santos Neto, Luiz Sinésio da Silva Tavares, Fernanda Silveira Andrade, Rosângela Vieira Rosa, Thiago dos Santos |
author_facet | Corrêa, Hugo de Luca Alfaro-Magallanes, Víctor Manuel Moura, Sting Ray Gouveia Neves, Rodrigo Vanerson Passos Deus, Lysleine Alves Honorato, Fernando Sousa Silva, Victor Lopes Raab, Artur Temizio Oppelt Maia, Beatriz Carneiro Habbema Padula, Isabela Akaishi de Gusmão Alves, Lucas Santos Machado, Rafaela Araújo Reis, Andrea Lucena Prestes, Jonato Ferreira, Carlos Ernesto Santos Neto, Luiz Sinésio da Silva Tavares, Fernanda Silveira Andrade, Rosângela Vieira Rosa, Thiago dos Santos |
author_sort | Corrêa, Hugo de Luca |
collection | PubMed |
description | We sought to investigate the effects of resistance training (RT) combined with erythropoietin (EPO) and iron sulfate on the hemoglobin, hepcidin, ferritin, iron status, and inflammatory profile in older individuals with end-stage renal disease (ESRD). ESRD patients (n: 157; age: 66.8 ± 3.6; body mass: 73 ± 15; body mass index: 27 ± 3), were assigned to control (CTL; n: 76) and exercise groups (RT; n: 81). The CTL group was divided according to the iron treatment received: without iron treatment (CTL—none; n = 19), treated only with iron sulfate or EPO (CTL—EPO or IRON; n = 19), and treated with both iron sulfate and EPO (CTL—EPO + IRON; n = 76). The RT group followed the same pattern: (RT—none; n = 20), (RT—EPO or IRON; n = 18), and (RT—EPO + IRON; n = 86). RT consisted of 24 weeks/3 days per week at moderate intensity of full-body resistance exercises prior to the hemodialysis section. The RT group, regardless of the iron treatment, improved iron metabolism in older individuals with ESRD. These results provide some clues on the effects of RT and its combination with EPO and iron sulfate in this population, highlighting RT as an important coadjutant in ESRD-iron deficiency. |
format | Online Article Text |
id | pubmed-8471184 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-84711842021-09-27 Does the Combined Effect of Resistance Training with EPO and Iron Sulfate Improve Iron Metabolism in Older Individuals with End-Stage Renal Disease? Corrêa, Hugo de Luca Alfaro-Magallanes, Víctor Manuel Moura, Sting Ray Gouveia Neves, Rodrigo Vanerson Passos Deus, Lysleine Alves Honorato, Fernando Sousa Silva, Victor Lopes Raab, Artur Temizio Oppelt Maia, Beatriz Carneiro Habbema Padula, Isabela Akaishi de Gusmão Alves, Lucas Santos Machado, Rafaela Araújo Reis, Andrea Lucena Prestes, Jonato Ferreira, Carlos Ernesto Santos Neto, Luiz Sinésio da Silva Tavares, Fernanda Silveira Andrade, Rosângela Vieira Rosa, Thiago dos Santos Nutrients Article We sought to investigate the effects of resistance training (RT) combined with erythropoietin (EPO) and iron sulfate on the hemoglobin, hepcidin, ferritin, iron status, and inflammatory profile in older individuals with end-stage renal disease (ESRD). ESRD patients (n: 157; age: 66.8 ± 3.6; body mass: 73 ± 15; body mass index: 27 ± 3), were assigned to control (CTL; n: 76) and exercise groups (RT; n: 81). The CTL group was divided according to the iron treatment received: without iron treatment (CTL—none; n = 19), treated only with iron sulfate or EPO (CTL—EPO or IRON; n = 19), and treated with both iron sulfate and EPO (CTL—EPO + IRON; n = 76). The RT group followed the same pattern: (RT—none; n = 20), (RT—EPO or IRON; n = 18), and (RT—EPO + IRON; n = 86). RT consisted of 24 weeks/3 days per week at moderate intensity of full-body resistance exercises prior to the hemodialysis section. The RT group, regardless of the iron treatment, improved iron metabolism in older individuals with ESRD. These results provide some clues on the effects of RT and its combination with EPO and iron sulfate in this population, highlighting RT as an important coadjutant in ESRD-iron deficiency. MDPI 2021-09-18 /pmc/articles/PMC8471184/ /pubmed/34579127 http://dx.doi.org/10.3390/nu13093250 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Corrêa, Hugo de Luca Alfaro-Magallanes, Víctor Manuel Moura, Sting Ray Gouveia Neves, Rodrigo Vanerson Passos Deus, Lysleine Alves Honorato, Fernando Sousa Silva, Victor Lopes Raab, Artur Temizio Oppelt Maia, Beatriz Carneiro Habbema Padula, Isabela Akaishi de Gusmão Alves, Lucas Santos Machado, Rafaela Araújo Reis, Andrea Lucena Prestes, Jonato Ferreira, Carlos Ernesto Santos Neto, Luiz Sinésio da Silva Tavares, Fernanda Silveira Andrade, Rosângela Vieira Rosa, Thiago dos Santos Does the Combined Effect of Resistance Training with EPO and Iron Sulfate Improve Iron Metabolism in Older Individuals with End-Stage Renal Disease? |
title | Does the Combined Effect of Resistance Training with EPO and Iron Sulfate Improve Iron Metabolism in Older Individuals with End-Stage Renal Disease? |
title_full | Does the Combined Effect of Resistance Training with EPO and Iron Sulfate Improve Iron Metabolism in Older Individuals with End-Stage Renal Disease? |
title_fullStr | Does the Combined Effect of Resistance Training with EPO and Iron Sulfate Improve Iron Metabolism in Older Individuals with End-Stage Renal Disease? |
title_full_unstemmed | Does the Combined Effect of Resistance Training with EPO and Iron Sulfate Improve Iron Metabolism in Older Individuals with End-Stage Renal Disease? |
title_short | Does the Combined Effect of Resistance Training with EPO and Iron Sulfate Improve Iron Metabolism in Older Individuals with End-Stage Renal Disease? |
title_sort | does the combined effect of resistance training with epo and iron sulfate improve iron metabolism in older individuals with end-stage renal disease? |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471184/ https://www.ncbi.nlm.nih.gov/pubmed/34579127 http://dx.doi.org/10.3390/nu13093250 |
work_keys_str_mv | AT correahugodeluca doesthecombinedeffectofresistancetrainingwithepoandironsulfateimproveironmetabolisminolderindividualswithendstagerenaldisease AT alfaromagallanesvictormanuel doesthecombinedeffectofresistancetrainingwithepoandironsulfateimproveironmetabolisminolderindividualswithendstagerenaldisease AT mourastingraygouveia doesthecombinedeffectofresistancetrainingwithepoandironsulfateimproveironmetabolisminolderindividualswithendstagerenaldisease AT nevesrodrigovanersonpassos doesthecombinedeffectofresistancetrainingwithepoandironsulfateimproveironmetabolisminolderindividualswithendstagerenaldisease AT deuslysleinealves doesthecombinedeffectofresistancetrainingwithepoandironsulfateimproveironmetabolisminolderindividualswithendstagerenaldisease AT honoratofernandosousa doesthecombinedeffectofresistancetrainingwithepoandironsulfateimproveironmetabolisminolderindividualswithendstagerenaldisease AT silvavictorlopes doesthecombinedeffectofresistancetrainingwithepoandironsulfateimproveironmetabolisminolderindividualswithendstagerenaldisease AT raabarturtemiziooppelt doesthecombinedeffectofresistancetrainingwithepoandironsulfateimproveironmetabolisminolderindividualswithendstagerenaldisease AT maiabeatrizcarneirohabbema doesthecombinedeffectofresistancetrainingwithepoandironsulfateimproveironmetabolisminolderindividualswithendstagerenaldisease AT padulaisabelaakaishi doesthecombinedeffectofresistancetrainingwithepoandironsulfateimproveironmetabolisminolderindividualswithendstagerenaldisease AT degusmaoalveslucassantos doesthecombinedeffectofresistancetrainingwithepoandironsulfateimproveironmetabolisminolderindividualswithendstagerenaldisease AT machadorafaelaaraujo doesthecombinedeffectofresistancetrainingwithepoandironsulfateimproveironmetabolisminolderindividualswithendstagerenaldisease AT reisandrealucena doesthecombinedeffectofresistancetrainingwithepoandironsulfateimproveironmetabolisminolderindividualswithendstagerenaldisease AT prestesjonato doesthecombinedeffectofresistancetrainingwithepoandironsulfateimproveironmetabolisminolderindividualswithendstagerenaldisease AT ferreiracarlosernestosantos doesthecombinedeffectofresistancetrainingwithepoandironsulfateimproveironmetabolisminolderindividualswithendstagerenaldisease AT netoluizsinesiodasilva doesthecombinedeffectofresistancetrainingwithepoandironsulfateimproveironmetabolisminolderindividualswithendstagerenaldisease AT tavaresfernandasilveira doesthecombinedeffectofresistancetrainingwithepoandironsulfateimproveironmetabolisminolderindividualswithendstagerenaldisease AT andraderosangelavieira doesthecombinedeffectofresistancetrainingwithepoandironsulfateimproveironmetabolisminolderindividualswithendstagerenaldisease AT rosathiagodossantos doesthecombinedeffectofresistancetrainingwithepoandironsulfateimproveironmetabolisminolderindividualswithendstagerenaldisease |