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Impact of DICER1 and DROSHA on the Angiogenic Capacity of Human Endothelial Cells

RNAi-mediated knockdown of DICER1 and DROSHA, enzymes critically involved in miRNA biogenesis, has been postulated to affect the homeostasis and the angiogenic capacity of human endothelial cells. To re-evaluate this issue, we reduced the expression of DICER1 or DROSHA by RNAi-mediated knockdown and...

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Detalles Bibliográficos
Autores principales: Braun, Heike, Hauke, Michael, Ripperger, Anne, Ihling, Christian, Fuszard, Matthew, Eckenstaler, Robert, Benndorf, Ralf A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471234/
https://www.ncbi.nlm.nih.gov/pubmed/34576018
http://dx.doi.org/10.3390/ijms22189855

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