Mechanistic Target of Rapamycin Complex 1 Signaling Links Hypoxia to Increased IGFBP-1 Phosphorylation in Primary Human Decidualized Endometrial Stromal Cells

Insulin-like growth factor-1 (IGF-1) bioavailability in pregnancy is governed by IGF binding protein (IGFBP-1) and its phosphorylation, which enhances the affinity of IGFBP-1 for the growth factor. The decidua is the predominant source of maternal IGFBP-1; however, the mechanisms regulating decidual...

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Detalles Bibliográficos
Autores principales: Nandi, Pinki, Jang, Chloe E., Biggar, Kyle, Halari, Chidambra D., Jansson, Thomas, Gupta, Madhulika B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471256/
https://www.ncbi.nlm.nih.gov/pubmed/34572595
http://dx.doi.org/10.3390/biom11091382

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