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A Computational Workflow for the Identification of Novel Fragments Acting as Inhibitors of the Activity of Protein Kinase CK1δ

Fragment-Based Drug Discovery (FBDD) has become, in recent years, a consolidated approach in the drug discovery process, leading to several drug candidates under investigation in clinical trials and some approved drugs. Among these successful applications of the FBDD approach, kinases represent a cl...

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Detalles Bibliográficos
Autores principales: Bolcato, Giovanni, Cescon, Eleonora, Pavan, Matteo, Bissaro, Maicol, Bassani, Davide, Federico, Stephanie, Spalluto, Giampiero, Sturlese, Mattia, Moro, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471300/
https://www.ncbi.nlm.nih.gov/pubmed/34575906
http://dx.doi.org/10.3390/ijms22189741