Heat Treatment Induced Specified Aggregation Morphology of Metoprolol Tartrate in Poly(ε-caprolactone) Matrix and the Drug Release Variation

Hot-melt blending has been widely used in the pharmaceutical industry to produce drug delivery systems, however, realizing the controlled drug release behavior of a hot-melt blended medicament it is still a tough challenge. In this study, we developed a simple and effective heat treatment method to...

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Detalles Bibliográficos
Autores principales: Liu, Zhiyu, Song, Hangling, Chen, Xia, Han, Aichun, Chen, Rong, Liu, Guiting, Guo, Shaoyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471319/
https://www.ncbi.nlm.nih.gov/pubmed/34577979
http://dx.doi.org/10.3390/polym13183076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471319/
https://www.ncbi.nlm.nih.gov/pubmed/34577979
http://dx.doi.org/10.3390/polym13183076

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