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Alternative Splicing Regulation of Low-Frequency Genetic Variants in Exon 2 of TREM2 in Alzheimer’s Disease by Splicing-Based Aggregation

TREM2 is among the most well-known Alzheimer’s disease (AD) risk genes; however, the functional roles of its AD-associated variants remain to be elucidated, and most known risk alleles are low-frequency variants whose investigation is challenging. Here, we utilized a splicing-guided aggregation meth...

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Detalles Bibliográficos
Autores principales:	Han, Seonggyun, Na, Yirang, Koh, Insong, Nho, Kwangsik, Lee, Younghee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471326/ https://www.ncbi.nlm.nih.gov/pubmed/34576031 http://dx.doi.org/10.3390/ijms22189865

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