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The Candidate IBD Risk Gene CCNY Is Dispensable for Intestinal Epithelial Homeostasis
The CCNY gene, which encodes cyclin Y, has been implicated in the pathogenesis of inflammatory bowel disease (IBD). Cyclin Y promotes Wnt/β-catenin signaling and autophagy, which are critical for intestinal epithelial cell (IEC) homeostasis, and may thereby contribute to wound repair in colitis. How...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471355/ https://www.ncbi.nlm.nih.gov/pubmed/34571979 http://dx.doi.org/10.3390/cells10092330 |