Marine Pyrrole Alkaloids

Nitrogen heterocycles are essential parts of the chemical machinery of life and often reveal intriguing structures. They are not only widespread in terrestrial habitats but can also frequently be found as natural products in the marine environment. This review highlights the important class of marin...

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Detalles Bibliográficos
Autores principales: Seipp, Kevin, Geske, Leander, Opatz, Till
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471394/
https://www.ncbi.nlm.nih.gov/pubmed/34564176
http://dx.doi.org/10.3390/md19090514
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author Seipp, Kevin
Geske, Leander
Opatz, Till
author_facet Seipp, Kevin
Geske, Leander
Opatz, Till
author_sort Seipp, Kevin
collection PubMed
description Nitrogen heterocycles are essential parts of the chemical machinery of life and often reveal intriguing structures. They are not only widespread in terrestrial habitats but can also frequently be found as natural products in the marine environment. This review highlights the important class of marine pyrrole alkaloids, well-known for their diverse biological activities. A broad overview of the marine pyrrole alkaloids with a focus on their isolation, biological activities, chemical synthesis, and derivatization covering the decade from 2010 to 2020 is provided. With relevant structural subclasses categorized, this review shall provide a clear and timely synopsis of this area.
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spelling pubmed-84713942021-09-27 Marine Pyrrole Alkaloids Seipp, Kevin Geske, Leander Opatz, Till Mar Drugs Review Nitrogen heterocycles are essential parts of the chemical machinery of life and often reveal intriguing structures. They are not only widespread in terrestrial habitats but can also frequently be found as natural products in the marine environment. This review highlights the important class of marine pyrrole alkaloids, well-known for their diverse biological activities. A broad overview of the marine pyrrole alkaloids with a focus on their isolation, biological activities, chemical synthesis, and derivatization covering the decade from 2010 to 2020 is provided. With relevant structural subclasses categorized, this review shall provide a clear and timely synopsis of this area. MDPI 2021-09-10 /pmc/articles/PMC8471394/ /pubmed/34564176 http://dx.doi.org/10.3390/md19090514 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Seipp, Kevin
Geske, Leander
Opatz, Till
Marine Pyrrole Alkaloids
title Marine Pyrrole Alkaloids
title_full Marine Pyrrole Alkaloids
title_fullStr Marine Pyrrole Alkaloids
title_full_unstemmed Marine Pyrrole Alkaloids
title_short Marine Pyrrole Alkaloids
title_sort marine pyrrole alkaloids
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471394/
https://www.ncbi.nlm.nih.gov/pubmed/34564176
http://dx.doi.org/10.3390/md19090514
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