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Deletion of NEMO Inhibits EMT and Reduces Metastasis in KPC Mice

SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma (PDAC) is highly metastatic and is expected to be the second leading cause of cancer-related deaths in the USA by 2030. In the current study, we investigated the role of NEMO/NF-κB signaling in the development and metastasis of PDAC by using the genet...

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Detalles Bibliográficos
Autores principales: Tsesmelis, Miltiadis, Tiwary, Kanishka, Steiger, Katja, Sperb, Nadine, Gerstenlauer, Melanie, Manfras, Uta, Maier, Harald J., Hermann, Patrick C., Chan, Lap Kwan, Wirth, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471477/
https://www.ncbi.nlm.nih.gov/pubmed/34572768
http://dx.doi.org/10.3390/cancers13184541