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Deletion of NEMO Inhibits EMT and Reduces Metastasis in KPC Mice
SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma (PDAC) is highly metastatic and is expected to be the second leading cause of cancer-related deaths in the USA by 2030. In the current study, we investigated the role of NEMO/NF-κB signaling in the development and metastasis of PDAC by using the genet...
Autores principales: | Tsesmelis, Miltiadis, Tiwary, Kanishka, Steiger, Katja, Sperb, Nadine, Gerstenlauer, Melanie, Manfras, Uta, Maier, Harald J., Hermann, Patrick C., Chan, Lap Kwan, Wirth, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471477/ https://www.ncbi.nlm.nih.gov/pubmed/34572768 http://dx.doi.org/10.3390/cancers13184541 |
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