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Ishige okamurae Ameliorates Methylglyoxal-Induced Nephrotoxicity via Reducing Oxidative Stress, RAGE Protein Expression, and Modulating MAPK, Nrf2/ARE Signaling Pathway in Mouse Glomerular Mesangial Cells
Advanced glycation end-products (AGEs) such as methylglyoxal (MGO) play a vital role in the pathogenesis of nephropathy, a diabetic complication. In the present study, we evaluated the anti-glycation and renal protective properties of Ishige okamurae extract (IOE) against AGE-induced oxidative stres...
Autores principales: | Kim, Mingyeong, Cho, Chiheung, Lee, Changjun, Ryu, Bomi, Kim, Sera, Hur, Jinyoung, Lee, Sang-Hoon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471766/ https://www.ncbi.nlm.nih.gov/pubmed/34574110 http://dx.doi.org/10.3390/foods10092000 |
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