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Poly (Ethylene Glycol) Methyl Ether Methacrylate-Based Hydrogel and Cerium(IV) Oxide Nanoparticles as Ophthalmic Lens Material

The functional hydrogel lens containing 2-hydroxyethylmethacrylate (HEMA) was manufactured by thermal polymerization. The physical properties of the produced hydrogel lens were measured and analyzed. In this study, HEMA, ethylene glycol dimethacrylate (EGDMA), and azobisisobutyronitrile (AIBN) were...

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Autores principales: Lee, Min-Jae, Park, Seon-Young, Sung, A-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471772/
https://www.ncbi.nlm.nih.gov/pubmed/34577754
http://dx.doi.org/10.3390/mi12091111
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author Lee, Min-Jae
Park, Seon-Young
Sung, A-Young
author_facet Lee, Min-Jae
Park, Seon-Young
Sung, A-Young
author_sort Lee, Min-Jae
collection PubMed
description The functional hydrogel lens containing 2-hydroxyethylmethacrylate (HEMA) was manufactured by thermal polymerization. The physical properties of the produced hydrogel lens were measured and analyzed. In this study, HEMA, ethylene glycol dimethacrylate (EGDMA), and azobisisobutyronitrile (AIBN) were used for thermal copolymerization. Additionally, poly (ethylene glycol) methyl ether methacrylate (PEGMEMA), 3-(Triethoxysilyl) propyl isocyanate (TEPI), and cerium(Ⅳ) oxide nanoparticles were used as additives to make a functional hydrogel lens. The mixture was heated at 100 °C for 90 min to produce the hydrogel ophthalmic lens by the cast mold method. The resulting physical properties showed that the water content and refractive index of the sample were in the ranges of 38.06~42.11% and 1.426~1.436, respectively. The addition of cerium oxide nanoparticles lowered the contact angle and allowed the hydrogel lens to block UV light. The tensile strength was also improved by 52.13% through cerium oxide nanoparticles, and up to 123.4% by using TEPI. Based on the results of this study, the produced ophthalmic lens is suitable for durable, UV-blocking high-performance lenses.
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spelling pubmed-84717722021-09-28 Poly (Ethylene Glycol) Methyl Ether Methacrylate-Based Hydrogel and Cerium(IV) Oxide Nanoparticles as Ophthalmic Lens Material Lee, Min-Jae Park, Seon-Young Sung, A-Young Micromachines (Basel) Article The functional hydrogel lens containing 2-hydroxyethylmethacrylate (HEMA) was manufactured by thermal polymerization. The physical properties of the produced hydrogel lens were measured and analyzed. In this study, HEMA, ethylene glycol dimethacrylate (EGDMA), and azobisisobutyronitrile (AIBN) were used for thermal copolymerization. Additionally, poly (ethylene glycol) methyl ether methacrylate (PEGMEMA), 3-(Triethoxysilyl) propyl isocyanate (TEPI), and cerium(Ⅳ) oxide nanoparticles were used as additives to make a functional hydrogel lens. The mixture was heated at 100 °C for 90 min to produce the hydrogel ophthalmic lens by the cast mold method. The resulting physical properties showed that the water content and refractive index of the sample were in the ranges of 38.06~42.11% and 1.426~1.436, respectively. The addition of cerium oxide nanoparticles lowered the contact angle and allowed the hydrogel lens to block UV light. The tensile strength was also improved by 52.13% through cerium oxide nanoparticles, and up to 123.4% by using TEPI. Based on the results of this study, the produced ophthalmic lens is suitable for durable, UV-blocking high-performance lenses. MDPI 2021-09-16 /pmc/articles/PMC8471772/ /pubmed/34577754 http://dx.doi.org/10.3390/mi12091111 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lee, Min-Jae
Park, Seon-Young
Sung, A-Young
Poly (Ethylene Glycol) Methyl Ether Methacrylate-Based Hydrogel and Cerium(IV) Oxide Nanoparticles as Ophthalmic Lens Material
title Poly (Ethylene Glycol) Methyl Ether Methacrylate-Based Hydrogel and Cerium(IV) Oxide Nanoparticles as Ophthalmic Lens Material
title_full Poly (Ethylene Glycol) Methyl Ether Methacrylate-Based Hydrogel and Cerium(IV) Oxide Nanoparticles as Ophthalmic Lens Material
title_fullStr Poly (Ethylene Glycol) Methyl Ether Methacrylate-Based Hydrogel and Cerium(IV) Oxide Nanoparticles as Ophthalmic Lens Material
title_full_unstemmed Poly (Ethylene Glycol) Methyl Ether Methacrylate-Based Hydrogel and Cerium(IV) Oxide Nanoparticles as Ophthalmic Lens Material
title_short Poly (Ethylene Glycol) Methyl Ether Methacrylate-Based Hydrogel and Cerium(IV) Oxide Nanoparticles as Ophthalmic Lens Material
title_sort poly (ethylene glycol) methyl ether methacrylate-based hydrogel and cerium(iv) oxide nanoparticles as ophthalmic lens material
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471772/
https://www.ncbi.nlm.nih.gov/pubmed/34577754
http://dx.doi.org/10.3390/mi12091111
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