3D Model of the Early Melanoma Microenvironment Captures Macrophage Transition into a Tumor-Promoting Phenotype

SIMPLE SUMMARY: We developed a “tumor-in-a-dish” experimental system to study the early events favoring tumor growth and suppression of the immune response in metastatic melanoma. We combined murine melanoma tumor cells with fibroblasts and macrophages in a 3D collagen matrix and characterized how i...

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Detalles Bibliográficos
Autores principales: Pizzurro, Gabriela A., Liu, Chang, Bridges, Kathryn, Alexander, Amanda F., Huang, Alice, Baskaran, Janani P., Ramseier, Julie, Bosenberg, Marcus W., Mak, Michael, Miller-Jensen, Kathryn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471848/
https://www.ncbi.nlm.nih.gov/pubmed/34572807
http://dx.doi.org/10.3390/cancers13184579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471848/
https://www.ncbi.nlm.nih.gov/pubmed/34572807
http://dx.doi.org/10.3390/cancers13184579

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