Current Status of HIV-1 Vaccines

HIV-1 infection and its progression to AIDS remains a significant global health challenge, particularly for low-income countries. Developing a vaccine to prevent HIV-1 infections has proven to be immensely challenging with complex biological acquisition and infection, unforeseen clinical trial disap...

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Autores principales: Hargrave, Anna, Mustafa, Abu Salim, Hanif, Asma, Tunio, Javed H., Hanif, Shumaila Nida M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471857/
https://www.ncbi.nlm.nih.gov/pubmed/34579263
http://dx.doi.org/10.3390/vaccines9091026
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author Hargrave, Anna
Mustafa, Abu Salim
Hanif, Asma
Tunio, Javed H.
Hanif, Shumaila Nida M.
author_facet Hargrave, Anna
Mustafa, Abu Salim
Hanif, Asma
Tunio, Javed H.
Hanif, Shumaila Nida M.
author_sort Hargrave, Anna
collection PubMed
description HIV-1 infection and its progression to AIDS remains a significant global health challenge, particularly for low-income countries. Developing a vaccine to prevent HIV-1 infections has proven to be immensely challenging with complex biological acquisition and infection, unforeseen clinical trial disappointments, and funding issues. This paper discusses important landmarks of progress in HIV-1 vaccine development, various vaccine strategies, and clinical trials.
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spelling pubmed-84718572021-09-28 Current Status of HIV-1 Vaccines Hargrave, Anna Mustafa, Abu Salim Hanif, Asma Tunio, Javed H. Hanif, Shumaila Nida M. Vaccines (Basel) Review HIV-1 infection and its progression to AIDS remains a significant global health challenge, particularly for low-income countries. Developing a vaccine to prevent HIV-1 infections has proven to be immensely challenging with complex biological acquisition and infection, unforeseen clinical trial disappointments, and funding issues. This paper discusses important landmarks of progress in HIV-1 vaccine development, various vaccine strategies, and clinical trials. MDPI 2021-09-16 /pmc/articles/PMC8471857/ /pubmed/34579263 http://dx.doi.org/10.3390/vaccines9091026 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Hargrave, Anna
Mustafa, Abu Salim
Hanif, Asma
Tunio, Javed H.
Hanif, Shumaila Nida M.
Current Status of HIV-1 Vaccines
title Current Status of HIV-1 Vaccines
title_full Current Status of HIV-1 Vaccines
title_fullStr Current Status of HIV-1 Vaccines
title_full_unstemmed Current Status of HIV-1 Vaccines
title_short Current Status of HIV-1 Vaccines
title_sort current status of hiv-1 vaccines
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471857/
https://www.ncbi.nlm.nih.gov/pubmed/34579263
http://dx.doi.org/10.3390/vaccines9091026
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