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Nonwoven Releasing Propolis as a Potential New Wound Healing Method—A Review

Wound healing poses a serious therapeutic problem. Methods which accelerate tissue regeneration and minimize or eliminate complications are constantly being sought. This paper is aimed at evaluation of the potential use of biodegradable polymer nonwovens releasing propolis as wound healing dressings...

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Detalles Bibliográficos
Autores principales: Stojko, Mateusz, Wolny, Daniel, Włodarczyk, Jakub
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471897/
https://www.ncbi.nlm.nih.gov/pubmed/34577172
http://dx.doi.org/10.3390/molecules26185701
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author Stojko, Mateusz
Wolny, Daniel
Włodarczyk, Jakub
author_facet Stojko, Mateusz
Wolny, Daniel
Włodarczyk, Jakub
author_sort Stojko, Mateusz
collection PubMed
description Wound healing poses a serious therapeutic problem. Methods which accelerate tissue regeneration and minimize or eliminate complications are constantly being sought. This paper is aimed at evaluation of the potential use of biodegradable polymer nonwovens releasing propolis as wound healing dressings, based on the literature data. Propolis is honeybee product with antioxidant, antibacterial, antifungal, anticancer, anti-inflammatory, analgesic, and regenerative properties. Controlled release of this substance throughout the healing should promote healing process, reduce the risk of wound infection, and improve aesthetic effect. The use of biodegradable aliphatic polyesters and polyester carbonates as a propolis carrier eliminates the problem of local drug administration and dressing changes. Well-known degradation processes and kinetics of the active substance release allows the selection of the material composition appropriate to the therapy. The electrospinning method allows the production of nonwovens that protect the wound against mechanical damage. Moreover, this processing technique enables adjusting product properties by modifying the production parameters. It can be concluded that biodegradable polymer dressings, releasing a propolis, may find potential application in the treatment of complicated wounds, as they may increase the effectiveness of treatment, as well as improve the patient’s life quality.
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spelling pubmed-84718972021-09-28 Nonwoven Releasing Propolis as a Potential New Wound Healing Method—A Review Stojko, Mateusz Wolny, Daniel Włodarczyk, Jakub Molecules Review Wound healing poses a serious therapeutic problem. Methods which accelerate tissue regeneration and minimize or eliminate complications are constantly being sought. This paper is aimed at evaluation of the potential use of biodegradable polymer nonwovens releasing propolis as wound healing dressings, based on the literature data. Propolis is honeybee product with antioxidant, antibacterial, antifungal, anticancer, anti-inflammatory, analgesic, and regenerative properties. Controlled release of this substance throughout the healing should promote healing process, reduce the risk of wound infection, and improve aesthetic effect. The use of biodegradable aliphatic polyesters and polyester carbonates as a propolis carrier eliminates the problem of local drug administration and dressing changes. Well-known degradation processes and kinetics of the active substance release allows the selection of the material composition appropriate to the therapy. The electrospinning method allows the production of nonwovens that protect the wound against mechanical damage. Moreover, this processing technique enables adjusting product properties by modifying the production parameters. It can be concluded that biodegradable polymer dressings, releasing a propolis, may find potential application in the treatment of complicated wounds, as they may increase the effectiveness of treatment, as well as improve the patient’s life quality. MDPI 2021-09-21 /pmc/articles/PMC8471897/ /pubmed/34577172 http://dx.doi.org/10.3390/molecules26185701 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Stojko, Mateusz
Wolny, Daniel
Włodarczyk, Jakub
Nonwoven Releasing Propolis as a Potential New Wound Healing Method—A Review
title Nonwoven Releasing Propolis as a Potential New Wound Healing Method—A Review
title_full Nonwoven Releasing Propolis as a Potential New Wound Healing Method—A Review
title_fullStr Nonwoven Releasing Propolis as a Potential New Wound Healing Method—A Review
title_full_unstemmed Nonwoven Releasing Propolis as a Potential New Wound Healing Method—A Review
title_short Nonwoven Releasing Propolis as a Potential New Wound Healing Method—A Review
title_sort nonwoven releasing propolis as a potential new wound healing method—a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471897/
https://www.ncbi.nlm.nih.gov/pubmed/34577172
http://dx.doi.org/10.3390/molecules26185701
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