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αβ-T Cells Engineered to Express γδ-T Cell Receptors Can Kill Neuroblastoma Organoids Independent of MHC-I Expression
Currently ~50% of patients with a diagnosis of high-risk neuroblastoma will not survive due to relapsing or refractory disease. Recent innovations in immunotherapy for solid tumors are highly promising, but the low MHC-I expression of neuroblastoma represents a major challenge for T cell-mediated im...
Autores principales: | Strijker, Josephine G. M., Pscheid, Ronja, Drent, Esther, van der Hoek, Jessica J. F., Koopmans, Bianca, Ober, Kimberley, van Hooff, Sander R., Kholosy, Waleed M., Cornel, Annelisa M., Coomans, Chris, Bisso, Andrea, van Loenen, Marleen M., Molenaar, Jan J., Wienke, Judith |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471928/ https://www.ncbi.nlm.nih.gov/pubmed/34575700 http://dx.doi.org/10.3390/jpm11090923 |
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