Cargando…

Simulation, In Vitro, and In Vivo Cytotoxicity Assessments of Methotrexate-Loaded pH-Responsive Nanocarriers

In this study, pH-responsive niosomal methotrexate (MTX) modified with ergosterol was prepared for potential anticancer application. The prepared formulation had a size of 176.7 ± 3.4 nm, zeta potential of −31.5 ± 2.6 mV, EE% of 76.9 ± 2.5%, and a pH-responsive behavior in two different pHs (5.4 and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Barani, Mahmood, Reza Hajinezhad, Mohammad, Sargazi, Saman, Zeeshan, Mahira, Rahdar, Abbas, Pandey, Sadanand, Khatami, Mehrdad, Zargari, Farshid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471936/ https://www.ncbi.nlm.nih.gov/pubmed/34578054 http://dx.doi.org/10.3390/polym13183153

Ejemplares similares

Preparation of pH-Responsive Vesicular Deferasirox: Evidence from In Silico, In Vitro, and In Vivo Evaluations
por: Barani, Mahmood, et al.
Publicado: (2021)

In vitro and in vivo anticancer effect of pH-responsive paclitaxel-loaded niosomes
por: Barani, Mahmood, et al.
Publicado: (2021)

DNA Based and Stimuli-Responsive Smart Nanocarrier for Diagnosis and Treatment of Cancer: Applications and Challenges
por: Sabir, Fakhara, et al.
Publicado: (2021)

Biochemical, Ameliorative and Cytotoxic Effects of Newly Synthesized Curcumin Microemulsions: Evidence from In Vitro and In Vivo Studies
por: Rahdar, Abbas, et al.
Publicado: (2021)

Recent Advances in Nanotechnology-Based Diagnosis and Treatments of Human Osteosarcoma
por: Barani, Mahmood, et al.
Publicado: (2021)

Multi-Functionalized Nanomaterials and Nanoparticles for Diagnosis and Treatment of Retinoblastoma
por: Arshad, Rabia, et al.
Publicado: (2021)

Theranostic Advances of Bionanomaterials against Gestational Diabetes Mellitus: A Preliminary Review
por: Barani, Mahmood, et al.
Publicado: (2021)

Nano-Based Theranostic Platforms for Breast Cancer: A Review of Latest Advancements
por: Arshad, Rabia, et al.
Publicado: (2022)

Nanomaterials in the Management of Gram-Negative Bacterial Infections
por: Barani, Mahmood, et al.
Publicado: (2021)

Nanomaterials for the Diagnosis and Treatment of Head and Neck Cancers: A Review
por: Ruiz-Pulido, Gustavo, et al.
Publicado: (2021)

Active Targeted Nanoparticles for Delivery of Poly(ADP-ribose) Polymerase (PARP) Inhibitors: A Preliminary Review
por: Sargazi, Saman, et al.
Publicado: (2021)

Application of Nanotechnology for Sensitive Detection of Low-Abundance Single-Nucleotide Variations in Genomic DNA: A Review
por: Mukhtar, Mahwash, et al.
Publicado: (2021)

Lignin-Stabilized Doxorubicin Microemulsions: Synthesis, Physical Characterization, and In Vitro Assessments
por: Rahdar, Abbas, et al.
Publicado: (2021)

Quantum Dots: Synthesis, Antibody Conjugation, and HER2-Receptor Targeting for Breast Cancer Therapy
por: Fatima, Iqra, et al.
Publicado: (2021)

Assessment of SnFe(2)O(4) Nanoparticles for Potential Application in Theranostics: Synthesis, Characterization, In Vitro, and In Vivo Toxicity
por: Sargazi, Saman, et al.
Publicado: (2021)

Stimuli-Responsive Polymeric Nanocarriers for Drug Delivery, Imaging, and Theragnosis
por: Das, Sabya Sachi, et al.
Publicado: (2020)

Nanotechnology in Bladder Cancer: Diagnosis and Treatment
por: Barani, Mahmood, et al.
Publicado: (2021)

Progress in the Application of Nanoparticles and Graphene as Drug Carriers and on the Diagnosis of Brain Infections
por: Barani, Mahmood, et al.
Publicado: (2021)

Amino Acids, Peptides, and Proteins: Implications for Nanotechnological Applications in Biosensing and Drug/Gene Delivery
por: Er, Simge, et al.
Publicado: (2021)

Novel Perspectives towards RNA-Based Nano-Theranostic Approaches for Cancer Management
por: Arshad, Rabia, et al.
Publicado: (2021)

Multifunctional folate receptor-targeting and pH-responsive nanocarriers loaded with methotrexate for treatment of rheumatoid arthritis
por: Zhao, Jinlong, et al.
Publicado: (2017)

Cabazitaxel-Loaded Nanocarriers for Cancer Therapy with Reduced Side Effects
por: Kommineni, Nagavendra, et al.
Publicado: (2019)

Methotrexate and Cytarabine—Loaded Nanocarriers for Multidrug Cancer Therapy. Spectroscopic Study
por: Pentak, Danuta, et al.
Publicado: (2016)

RETRACTED ARTICLE: Biosynthesis of Zn-doped CuFe(2)O(4) nanoparticles and their cytotoxic activity
por: Darvish, Maryam, et al.
Publicado: (2022)

Retraction Note: Biosynthesis of Zn-doped CuFe(2)O(4) nanoparticles and their cytotoxic activity
por: Darvish, Maryam, et al.
Publicado: (2023)

Nanomaterials for the Diagnosis and Treatment of Urinary Tract Infections
por: Qindeel, Maimoona, et al.
Publicado: (2021)

Methotrexate Gold Nanocarriers: Loading and Release Study: Its Activity in Colon and Lung Cancer Cells
por: Álvarez-González, Beatriz, et al.
Publicado: (2020)

Nanotreatment and Nanodiagnosis of Prostate Cancer: Recent Updates
por: Barani, Mahmood, et al.
Publicado: (2020)

Evaluation of cytotoxicity, loading, and release activity of paclitaxel loaded-porphyrin based metal-organic framework (PCN-600)
por: Hamidian, Khadijeh, et al.
Publicado: (2022)

Advances of liposomal mediated nanocarriers for the treatment of dermatophyte infections
por: Ayatollahi Mousavi, Seyed Amin, et al.
Publicado: (2023)

Insights on Ultrafiltration-Based Separation for the Purification and Quantification of Methotrexate in Nanocarriers
por: Marques, Sara S., et al.
Publicado: (2020)

Cannabinoid derivate-loaded PLGA nanocarriers for oral administration: formulation, characterization, and cytotoxicity studies
por: Martín-Banderas, Lucía, et al.
Publicado: (2012)

Synthesis of Al-Based Metal-Organic Framework in Water With Caffeic Acid Ligand and NaOH as Linker Sources With Highly Efficient Anticancer Treatment
por: Zeraati, Malihe, et al.
Publicado: (2021)

Biosynthesis of spinel nickel ferrite nanowhiskers and their biomedical applications
por: Alijani, Hajar Q., et al.
Publicado: (2021)

Application of Various Optical and Electrochemical Nanobiosensors for Detecting Cancer Antigen 125 (CA-125): A Review
por: Pourmadadi, Mehrab, et al.
Publicado: (2023)

Methotrexate-Loaded Gelatin and Polyvinyl Alcohol (Gel/PVA) Hydrogel as a pH-Sensitive Matrix
por: Akhlaq, Muhammad, et al.
Publicado: (2021)

pH-Responsive Nanocarriers in Cancer Therapy
por: AlSawaftah, Nour M., et al.
Publicado: (2022)

Evaluation of Carum-loaded Niosomes on Breast Cancer Cells:Physicochemical Properties, In Vitro Cytotoxicity, Flow Cytometric, DNA Fragmentation and Cell Migration Assay
por: Barani, Mahmood, et al.
Publicado: (2019)

Nanomaterials for the Diagnosis and Treatment of Inflammatory Arthritis
por: Hosseinikhah, Seyedeh Maryam, et al.
Publicado: (2021)

Application of Green Gold Nanoparticles in Cancer Therapy and Diagnosis
por: Sargazi, Saman, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_phq8n111r1k23goebkg9rad2u2