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Hospital Wastewater—Source of Specific Micropollutants, Antibiotic-Resistant Microorganisms, Viruses, and Their Elimination

Municipal wastewaters can generally provide real-time information on drug consumption, the incidence of specific diseases, or establish exposure to certain agents and determine some lifestyle consequences. From this point of view, wastewater-based epidemiology represents a modern diagnostic tool for...

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Autores principales: Mackuľak, Tomáš, Cverenkárová, Klára, Vojs Staňová, Andrea, Fehér, Miroslav, Tamáš, Michal, Škulcová, Andrea Bútor, Gál, Miroslav, Naumowicz, Monika, Špalková, Viera, Bírošová, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471966/
https://www.ncbi.nlm.nih.gov/pubmed/34572652
http://dx.doi.org/10.3390/antibiotics10091070
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author Mackuľak, Tomáš
Cverenkárová, Klára
Vojs Staňová, Andrea
Fehér, Miroslav
Tamáš, Michal
Škulcová, Andrea Bútor
Gál, Miroslav
Naumowicz, Monika
Špalková, Viera
Bírošová, Lucia
author_facet Mackuľak, Tomáš
Cverenkárová, Klára
Vojs Staňová, Andrea
Fehér, Miroslav
Tamáš, Michal
Škulcová, Andrea Bútor
Gál, Miroslav
Naumowicz, Monika
Špalková, Viera
Bírošová, Lucia
author_sort Mackuľak, Tomáš
collection PubMed
description Municipal wastewaters can generally provide real-time information on drug consumption, the incidence of specific diseases, or establish exposure to certain agents and determine some lifestyle consequences. From this point of view, wastewater-based epidemiology represents a modern diagnostic tool for describing the health status of a certain part of the population in a specific region. Hospital wastewater is a complex mixture of pharmaceuticals, illegal drugs, and their metabolites as well as different susceptible and antibiotic-resistant microorganisms, including viruses. Many studies pointed out that wastewater from healthcare facilities (including hospital wastewater), significantly contributes to higher loads of micropollutants, including bacteria and viruses, in municipal wastewater. In addition, such a mixture can increase the selective pressure on bacteria, thus contributing to the development and dissemination of antimicrobial resistance. Because many pharmaceuticals, drugs, and microorganisms can pass through wastewater treatment plants without any significant change in their structure and toxicity and enter surface waters, treatment technologies need to be improved. This short review summarizes the recent knowledge from studies on micropollutants, pathogens, antibiotic-resistant bacteria, and viruses (including SARS-CoV-2) in wastewater from healthcare facilities. It also proposes several possibilities for improving the wastewater treatment process in terms of efficiency as well as economy.
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spelling pubmed-84719662021-09-28 Hospital Wastewater—Source of Specific Micropollutants, Antibiotic-Resistant Microorganisms, Viruses, and Their Elimination Mackuľak, Tomáš Cverenkárová, Klára Vojs Staňová, Andrea Fehér, Miroslav Tamáš, Michal Škulcová, Andrea Bútor Gál, Miroslav Naumowicz, Monika Špalková, Viera Bírošová, Lucia Antibiotics (Basel) Review Municipal wastewaters can generally provide real-time information on drug consumption, the incidence of specific diseases, or establish exposure to certain agents and determine some lifestyle consequences. From this point of view, wastewater-based epidemiology represents a modern diagnostic tool for describing the health status of a certain part of the population in a specific region. Hospital wastewater is a complex mixture of pharmaceuticals, illegal drugs, and their metabolites as well as different susceptible and antibiotic-resistant microorganisms, including viruses. Many studies pointed out that wastewater from healthcare facilities (including hospital wastewater), significantly contributes to higher loads of micropollutants, including bacteria and viruses, in municipal wastewater. In addition, such a mixture can increase the selective pressure on bacteria, thus contributing to the development and dissemination of antimicrobial resistance. Because many pharmaceuticals, drugs, and microorganisms can pass through wastewater treatment plants without any significant change in their structure and toxicity and enter surface waters, treatment technologies need to be improved. This short review summarizes the recent knowledge from studies on micropollutants, pathogens, antibiotic-resistant bacteria, and viruses (including SARS-CoV-2) in wastewater from healthcare facilities. It also proposes several possibilities for improving the wastewater treatment process in terms of efficiency as well as economy. MDPI 2021-09-04 /pmc/articles/PMC8471966/ /pubmed/34572652 http://dx.doi.org/10.3390/antibiotics10091070 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Mackuľak, Tomáš
Cverenkárová, Klára
Vojs Staňová, Andrea
Fehér, Miroslav
Tamáš, Michal
Škulcová, Andrea Bútor
Gál, Miroslav
Naumowicz, Monika
Špalková, Viera
Bírošová, Lucia
Hospital Wastewater—Source of Specific Micropollutants, Antibiotic-Resistant Microorganisms, Viruses, and Their Elimination
title Hospital Wastewater—Source of Specific Micropollutants, Antibiotic-Resistant Microorganisms, Viruses, and Their Elimination
title_full Hospital Wastewater—Source of Specific Micropollutants, Antibiotic-Resistant Microorganisms, Viruses, and Their Elimination
title_fullStr Hospital Wastewater—Source of Specific Micropollutants, Antibiotic-Resistant Microorganisms, Viruses, and Their Elimination
title_full_unstemmed Hospital Wastewater—Source of Specific Micropollutants, Antibiotic-Resistant Microorganisms, Viruses, and Their Elimination
title_short Hospital Wastewater—Source of Specific Micropollutants, Antibiotic-Resistant Microorganisms, Viruses, and Their Elimination
title_sort hospital wastewater—source of specific micropollutants, antibiotic-resistant microorganisms, viruses, and their elimination
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8471966/
https://www.ncbi.nlm.nih.gov/pubmed/34572652
http://dx.doi.org/10.3390/antibiotics10091070
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