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Simultaneous Exposure to Angiostrongylus vasorum and Vector-Borne Pathogens in Dogs from Italy

Several drivers have recently fostered the expansion of Angiostrongylus vasorum throughout Europe, where Vector-Borne Pathogens (VBPs) are also spreading. However, the level of simultaneous risk of infection is still unknown in canine populations. This study evaluated the simultaneous exposure to A....

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Autores principales: Morelli, Simone, Gori, Francesca, Colombo, Mariasole, Traversa, Donato, Sarrocco, Giulia, Simonato, Giulia, Nespeca, Chiara, Di Cesare, Angela, Frangipane di Regalbono, Antonio, Veronesi, Fabrizia, Russi, Ilaria, Schnyder, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472057/
https://www.ncbi.nlm.nih.gov/pubmed/34578232
http://dx.doi.org/10.3390/pathogens10091200
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author Morelli, Simone
Gori, Francesca
Colombo, Mariasole
Traversa, Donato
Sarrocco, Giulia
Simonato, Giulia
Nespeca, Chiara
Di Cesare, Angela
Frangipane di Regalbono, Antonio
Veronesi, Fabrizia
Russi, Ilaria
Schnyder, Manuela
author_facet Morelli, Simone
Gori, Francesca
Colombo, Mariasole
Traversa, Donato
Sarrocco, Giulia
Simonato, Giulia
Nespeca, Chiara
Di Cesare, Angela
Frangipane di Regalbono, Antonio
Veronesi, Fabrizia
Russi, Ilaria
Schnyder, Manuela
author_sort Morelli, Simone
collection PubMed
description Several drivers have recently fostered the expansion of Angiostrongylus vasorum throughout Europe, where Vector-Borne Pathogens (VBPs) are also spreading. However, the level of simultaneous risk of infection is still unknown in canine populations. This study evaluated the simultaneous exposure to A. vasorum and major canine VBPs in dogs of Italy. Sera of 294 dogs were subjected to two ELISAs, detecting A. vasorum circulating antigens and antibodies against the parasite, and to the following assays: (i) SNAP® 4DX (IDEXX Laboratories Inc.) detecting Dirofilaria immitis antigens, and antibodies vs. Borrelia burgdorferi, Anaplasma spp. and Ehrlichia spp. and (ii) IFAT for the detection of antibodies vs. Leishmania infantum, Babesia canis and Rickettsia conorii. Twenty-two (7.5%, CI: 4.8–11.1%) and six (2%, CI: 0.7–4.4%) dogs scored positive for circulating A. vasorum antibodies and antigens, respectively. Seventeen dogs (5.8%, CI: 3.4–9.1%) were positive for A. vasorum antibodies + at least one VBP, three (1%, CI: 0.2–3%) for A. vasorum antigen + at least one VBP, while one dog (0.3%, CI: 0.01–1.88%) was positive for A. vasorum antigen + A. vasorum antibodies + B. canis antibodies. These results show that dogs living in different regions of Italy are at risk of simultaneous infections with both A. vasorum and VBPs. Despite the same scenario being likely in other countries of Europe, the current knowledge is scant. Therefore, further studies are warranted to amplify current epizootiological information and to understand whether control programs should be improved.
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spelling pubmed-84720572021-09-28 Simultaneous Exposure to Angiostrongylus vasorum and Vector-Borne Pathogens in Dogs from Italy Morelli, Simone Gori, Francesca Colombo, Mariasole Traversa, Donato Sarrocco, Giulia Simonato, Giulia Nespeca, Chiara Di Cesare, Angela Frangipane di Regalbono, Antonio Veronesi, Fabrizia Russi, Ilaria Schnyder, Manuela Pathogens Article Several drivers have recently fostered the expansion of Angiostrongylus vasorum throughout Europe, where Vector-Borne Pathogens (VBPs) are also spreading. However, the level of simultaneous risk of infection is still unknown in canine populations. This study evaluated the simultaneous exposure to A. vasorum and major canine VBPs in dogs of Italy. Sera of 294 dogs were subjected to two ELISAs, detecting A. vasorum circulating antigens and antibodies against the parasite, and to the following assays: (i) SNAP® 4DX (IDEXX Laboratories Inc.) detecting Dirofilaria immitis antigens, and antibodies vs. Borrelia burgdorferi, Anaplasma spp. and Ehrlichia spp. and (ii) IFAT for the detection of antibodies vs. Leishmania infantum, Babesia canis and Rickettsia conorii. Twenty-two (7.5%, CI: 4.8–11.1%) and six (2%, CI: 0.7–4.4%) dogs scored positive for circulating A. vasorum antibodies and antigens, respectively. Seventeen dogs (5.8%, CI: 3.4–9.1%) were positive for A. vasorum antibodies + at least one VBP, three (1%, CI: 0.2–3%) for A. vasorum antigen + at least one VBP, while one dog (0.3%, CI: 0.01–1.88%) was positive for A. vasorum antigen + A. vasorum antibodies + B. canis antibodies. These results show that dogs living in different regions of Italy are at risk of simultaneous infections with both A. vasorum and VBPs. Despite the same scenario being likely in other countries of Europe, the current knowledge is scant. Therefore, further studies are warranted to amplify current epizootiological information and to understand whether control programs should be improved. MDPI 2021-09-15 /pmc/articles/PMC8472057/ /pubmed/34578232 http://dx.doi.org/10.3390/pathogens10091200 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Morelli, Simone
Gori, Francesca
Colombo, Mariasole
Traversa, Donato
Sarrocco, Giulia
Simonato, Giulia
Nespeca, Chiara
Di Cesare, Angela
Frangipane di Regalbono, Antonio
Veronesi, Fabrizia
Russi, Ilaria
Schnyder, Manuela
Simultaneous Exposure to Angiostrongylus vasorum and Vector-Borne Pathogens in Dogs from Italy
title Simultaneous Exposure to Angiostrongylus vasorum and Vector-Borne Pathogens in Dogs from Italy
title_full Simultaneous Exposure to Angiostrongylus vasorum and Vector-Borne Pathogens in Dogs from Italy
title_fullStr Simultaneous Exposure to Angiostrongylus vasorum and Vector-Borne Pathogens in Dogs from Italy
title_full_unstemmed Simultaneous Exposure to Angiostrongylus vasorum and Vector-Borne Pathogens in Dogs from Italy
title_short Simultaneous Exposure to Angiostrongylus vasorum and Vector-Borne Pathogens in Dogs from Italy
title_sort simultaneous exposure to angiostrongylus vasorum and vector-borne pathogens in dogs from italy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472057/
https://www.ncbi.nlm.nih.gov/pubmed/34578232
http://dx.doi.org/10.3390/pathogens10091200
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