Time-Dependent Protective and Pro-Resolving Effects of FPR2 Agonists on Lipopolysaccharide-Exposed Microglia Cells Involve Inhibition of NF-κB and MAPKs Pathways

Prolonged or excessive microglial activation may lead to disturbances in the resolution of inflammation (RoI). The importance of specialized pro-resolving lipid mediators (SPMs) in RoI has been highlighted. Among them, lipoxins (LXA4) and aspirin-triggered lipoxin A4 (AT-LXA4) mediate beneficial res...

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Detalles Bibliográficos
Autores principales: Tylek, Kinga, Trojan, Ewa, Leśkiewicz, Monika, Regulska, Magdalena, Bryniarska, Natalia, Curzytek, Katarzyna, Lacivita, Enza, Leopoldo, Marcello, Basta-Kaim, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472089/
https://www.ncbi.nlm.nih.gov/pubmed/34572022
http://dx.doi.org/10.3390/cells10092373

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