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Tick-Borne Encephalitis Virus (TBEV) Infection in Two Horses

A final diagnosis in a horse with clinical signs of encephalopathy can be challenging despite the use of extensive diagnostics. Clinical signs are often not pathognomonic and need to be interpreted in combination with (specific) laboratory results and epidemiological data of the geographical region...

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Autores principales: Conze, Theresa Maria, Bagó, Zoltán, Revilla-Fernández, Sandra, Schlegel, Jürgen, Goehring, Lutz S., Matiasek, Kaspar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472121/
https://www.ncbi.nlm.nih.gov/pubmed/34578356
http://dx.doi.org/10.3390/v13091775
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author Conze, Theresa Maria
Bagó, Zoltán
Revilla-Fernández, Sandra
Schlegel, Jürgen
Goehring, Lutz S.
Matiasek, Kaspar
author_facet Conze, Theresa Maria
Bagó, Zoltán
Revilla-Fernández, Sandra
Schlegel, Jürgen
Goehring, Lutz S.
Matiasek, Kaspar
author_sort Conze, Theresa Maria
collection PubMed
description A final diagnosis in a horse with clinical signs of encephalopathy can be challenging despite the use of extensive diagnostics. Clinical signs are often not pathognomonic and need to be interpreted in combination with (specific) laboratory results and epidemiological data of the geographical region of the origin of the case(s). Here we describe the diagnostic pathway of tick-borne encephalitis virus infection in two horses using established molecular diagnostic methods and a novel in situ hybridization technique to differentiate between regionally important/emerging diseases for central Europe: (i) hepatoencephalopathy, (ii) Borna disease virus, and (iii) West Nile virus infections.
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spelling pubmed-84721212021-09-28 Tick-Borne Encephalitis Virus (TBEV) Infection in Two Horses Conze, Theresa Maria Bagó, Zoltán Revilla-Fernández, Sandra Schlegel, Jürgen Goehring, Lutz S. Matiasek, Kaspar Viruses Article A final diagnosis in a horse with clinical signs of encephalopathy can be challenging despite the use of extensive diagnostics. Clinical signs are often not pathognomonic and need to be interpreted in combination with (specific) laboratory results and epidemiological data of the geographical region of the origin of the case(s). Here we describe the diagnostic pathway of tick-borne encephalitis virus infection in two horses using established molecular diagnostic methods and a novel in situ hybridization technique to differentiate between regionally important/emerging diseases for central Europe: (i) hepatoencephalopathy, (ii) Borna disease virus, and (iii) West Nile virus infections. MDPI 2021-09-06 /pmc/articles/PMC8472121/ /pubmed/34578356 http://dx.doi.org/10.3390/v13091775 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Conze, Theresa Maria
Bagó, Zoltán
Revilla-Fernández, Sandra
Schlegel, Jürgen
Goehring, Lutz S.
Matiasek, Kaspar
Tick-Borne Encephalitis Virus (TBEV) Infection in Two Horses
title Tick-Borne Encephalitis Virus (TBEV) Infection in Two Horses
title_full Tick-Borne Encephalitis Virus (TBEV) Infection in Two Horses
title_fullStr Tick-Borne Encephalitis Virus (TBEV) Infection in Two Horses
title_full_unstemmed Tick-Borne Encephalitis Virus (TBEV) Infection in Two Horses
title_short Tick-Borne Encephalitis Virus (TBEV) Infection in Two Horses
title_sort tick-borne encephalitis virus (tbev) infection in two horses
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472121/
https://www.ncbi.nlm.nih.gov/pubmed/34578356
http://dx.doi.org/10.3390/v13091775
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