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Primary Human Colon Epithelial Cells (pHCoEpiCs) Do Express the Shiga Toxin (Stx) Receptor Glycosphingolipids Gb3Cer and Gb4Cer and Are Largely Refractory but Not Resistant towards Stx

Shiga toxin (Stx) is released by enterohemorrhagic Escherichia coli (EHEC) into the human intestinal lumen and transferred across the colon epithelium to the circulation. Stx-mediated damage of human kidney and brain endothelial cells and renal epithelial cells is a renowned feature, while the sensi...

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Detalles Bibliográficos
Autores principales:	Detzner, Johanna, Püttmann, Charlotte, Pohlentz, Gottfried, Humpf, Hans-Ulrich, Mellmann, Alexander, Karch, Helge, Müthing, Johannes
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472147/ https://www.ncbi.nlm.nih.gov/pubmed/34576167 http://dx.doi.org/10.3390/ijms221810002

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