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Adipose Tissue Macrophages Modulate Obesity-Associated β Cell Adaptations through Secreted miRNA-Containing Extracellular Vesicles

Obesity induces an adaptive expansion of β cell mass and insulin secretion abnormality. Expansion of adipose tissue macrophages (ATMs) is a hallmark of obesity. Here, we assessed a novel role of ATMs in mediating obesity-induced β cell adaptation through the release of miRNA-containing extracellular...

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Detalles Bibliográficos
Autores principales: Gao, Hong, Luo, Zhenlong, Jin, Zhongmou, Ji, Yudong, Ying, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472266/
https://www.ncbi.nlm.nih.gov/pubmed/34572101
http://dx.doi.org/10.3390/cells10092451

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