A Conserved Hydrophobic Moiety and Helix–Helix Interactions Drive the Self-Assembly of the Incretin Analog Exendin-4

Exendin-4 is a pharmaceutical peptide used in the control of insulin secretion. Structural information on exendin-4 and related peptides especially on the level of quaternary structure is scarce. We present the first published association equilibria of exendin-4 directly measured by static and dynam...

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Detalles Bibliográficos
Autores principales: Wolff, Martin, Gast, Klaus, Evers, Andreas, Kurz, Michael, Pfeiffer-Marek, Stefania, Schüler, Anja, Seckler, Robert, Thalhammer, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472270/
https://www.ncbi.nlm.nih.gov/pubmed/34572518
http://dx.doi.org/10.3390/biom11091305

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