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Comprehensive Insight into Chemical Stability of Important Antidiabetic Drug Vildagliptin Using Chromatography (LC-UV and UHPLC-DAD-MS) and Spectroscopy (Mid-IR and NIR with PCA)

During forced degradation, the intrinsic stability of active pharmaceutical ingredients (APIs) could be determined and possible impurities that would occur during the shelf life of the drug substance or the drug product could be estimated. Vildagliptin belongs to relatively new oral antidiabetic dru...

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Detalles Bibliográficos
Autores principales: Gumieniczek, Anna, Berecka-Rycerz, Anna, Fornal, Emilia, Żyżyńska-Granica, Barbara, Granica, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472283/
https://www.ncbi.nlm.nih.gov/pubmed/34577104
http://dx.doi.org/10.3390/molecules26185632