Cargando…

Orally Administered Natural Lipid Nanoparticle-Loaded 6-Shogaol Shapes the Anti-Inflammatory Microbiota and Metabolome

The past decade has seen increasing interest in microbiota-targeting therapeutic strategies that aim to modulate the gut microbiota’s composition and/or function to treat chronic diseases, such as inflammatory bowel disease (IBD), metabolic symptoms, and obesity. While targeting the gut microbiota i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Chunhua, Long, Dingpei, Sung, Junsik, Alghoul, Zahra, Merlin, Didier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472296/ https://www.ncbi.nlm.nih.gov/pubmed/34575431 http://dx.doi.org/10.3390/pharmaceutics13091355

Ejemplares similares

Prevention of Colitis-Associated Cancer via Oral Administration of M13-Loaded Lipid Nanoparticles
por: Long, Dingpei, et al.
Publicado: (2023)

Prevention of Ulcerative Colitis by Autologous Metabolite Transfer from Colitogenic Microbiota Treated with Lipid Nanoparticles Encapsulating an Anti-Inflammatory Drug Candidate
por: Yang, Chunhua, et al.
Publicado: (2022)

Preparation and Characterization of IL-22 mRNA-loaded Lipid Nanoparticles
por: Alghoul, Zahra, et al.
Publicado: (2023)

The Current Status of Molecular Biomarkers for Inflammatory Bowel Disease
por: Alghoul, Zahra, et al.
Publicado: (2022)

Impact of PepT1 deletion on microbiota composition and colitis requires multiple generations
por: Viennois, Emilie, et al.
Publicado: (2020)

Glucuronidation of [6]-shogaol, [8]-shogaol and [10]-shogaol by human tissues and expressed UGT enzymes: identification of UGT2B7 as the major contributor
por: He, Liangliang, et al.
Publicado: (2018)

The possibility of using shogaol for treatment of ulcerative colitis
por: Hassan, Snur MA, et al.
Publicado: (2018)

Anti-inflammatory effect and signaling mechanism of 8-shogaol and 10-shogaol in a dextran sodium sulfate-induced colitis mouse model
por: Kim, Ha-Rim, et al.
Publicado: (2023)

Lipid-Based Drug Delivery Nanoplatforms for Colorectal Cancer Therapy
por: Yang, Chunhua, et al.
Publicado: (2020)

6-Shogaol and 10-Shogaol Synergize Curcumin in Ameliorating Proinflammatory Mediators via the Modulation of TLR4/TRAF6/MAPK and NFκB Translocation
por: Zhou, Xian, et al.
Publicado: (2023)

Benefits of Ginger and Its Constituent 6-Shogaol in Inhibiting Inflammatory Processes
por: Bischoff-Kont, Iris, et al.
Publicado: (2021)

Nanoparticle-Mediated Drug Delivery Systems For The Treatment Of IBD: Current Perspectives
por: Yang, Chunhua, et al.
Publicado: (2019)

Oral Gavage of Ginger Nanoparticle-Derived Lipid Vectors Carrying Dmt1 siRNA Blunts Iron Loading in Murine Hereditary Hemochromatosis
por: Wang, Xiaoyu, et al.
Publicado: (2019)

Effect of 6-Shogaol on the Glucose Uptake and Survival of HT1080 Fibrosarcoma Cells
por: Romero-Arias, Angie C., et al.
Publicado: (2019)

6-Shogaol Mitigates Sepsis-Associated Hepatic Injury through Transcriptional Regulation
por: Guo, Xiaoxuan, et al.
Publicado: (2021)

Histone Deacetylase Inhibitory Activity and Antiproliferative Potential of New [6]-Shogaol Derivatives
por: Phaosiri, Chanokbhorn, et al.
Publicado: (2022)

6-shogaol is a potential treatment for Head and Neck Squamous Cell Carcinoma
por: Hsu, Cheng-Ming, et al.
Publicado: (2023)

Shape Matters: Comprehensive Analysis of Star-Shaped Lipid Nanoparticles
por: Cao, Shuwen, et al.
Publicado: (2020)

10-Shogaol, an Antioxidant from Zingiber officinale for Skin Cell Proliferation and Migration Enhancer
por: Chen, Chung-Yi, et al.
Publicado: (2012)

6-Shogaol Overcomes Gefitinib Resistance via ER Stress in Ovarian Cancer Cells
por: Kim, Tae Woo, et al.
Publicado: (2023)

Effects of 6-Shogaol on Glucose Uptake and Intestinal Barrier Integrity in Caco-2 Cells
por: Jiao, Wenya, et al.
Publicado: (2023)

Anticancer perspective of 6-shogaol: anticancer properties, mechanism of action, synergism and delivery system
por: Jia, Yaoxia, et al.
Publicado: (2023)

Solid lipid nanoparticles to improve bioaccessibility and permeability of orally administered maslinic acid
por: Aguilera-Garrido, Aixa, et al.
Publicado: (2022)

Antioxidant hepatic lipid metabolism can be promoted by orally administered inorganic nanoparticles
por: Cai, Jie, et al.
Publicado: (2023)

Metabolomics analysis of plasma and adipose tissue samples from mice orally administered with polydextrose and correlations with cecal microbiota
por: Saarinen, Markku Tapani, et al.
Publicado: (2020)

Enhanced Oral Bioavailability, Anti-Tumor Activity and Hepatoprotective Effect of 6-Shogaol Loaded in a Type of Novel Micelles of Polyethylene Glycol and Linoleic Acid Conjugate
por: Zhang, Huiyun, et al.
Publicado: (2019)

6-Shogaol reduced chronic inflammatory response in the knees of rats treated with complete Freund's adjuvant
por: Levy, Arkene SA, et al.
Publicado: (2006)

Optimization of Extraction Conditions for the 6-Shogaol-rich Extract from Ginger (Zingiber officinale Roscoe)
por: Ok, Seon, et al.
Publicado: (2012)

Identification and characterization of [6]-shogaol from ginger as inhibitor of vascular smooth muscle cell proliferation
por: Liu, Rongxia, et al.
Publicado: (2015)

Anticancer effects of 6-shogaol via the AKT signaling pathway in oral squamous cell carcinoma
por: HUANG, Hai, et al.
Publicado: (2021)

6-Shogaol attenuated ethylene glycol and aluminium chloride induced urolithiasis and renal injuries in rodents
por: Afzal, Muhammad, et al.
Publicado: (2021)

Is 6-Shogaol an Effective Phytochemical for Patients With Lower-risk Myelodysplastic Syndrome? A Narrative Review
por: Ooi, Soo Liang, et al.
Publicado: (2021)

Recent advances in orally administered cell-specific nanotherapeutics for inflammatory bowel disease
por: Si, Xiao-Ying, et al.
Publicado: (2016)

Gut Microbiota-Modulated Metabolomic Profiling Shapes the Etiology and Pathogenesis of Autoimmune Diseases
por: Tsai, Yi-Wen, et al.
Publicado: (2021)

Preparation of Curcumin Solid Lipid Nanoparticles Loaded with Flower-Shaped Lactose for Lung Inhalation and Preliminary Evaluation of Cytotoxicity In Vitro
por: Li, Nan, et al.
Publicado: (2021)

Development of New Natural Lipid-Based Nanoparticles Loaded with Aluminum-Phthalocyanine for Photodynamic Therapy against Melanoma
por: Mello, Victor Carlos, et al.
Publicado: (2022)

Antibiofilm and Antivirulence Activities of 6-Gingerol and 6-Shogaol Against Candida albicans Due to Hyphal Inhibition
por: Lee, Jin-Hyung, et al.
Publicado: (2018)

Effect of Shogaol on the Expression of Intestinal Stem Cell Markers in Experimentally Induced Colitis in BALB/c Mice
por: Hassan, Snur M. A., et al.
Publicado: (2019)

Neuroprotective Effects of 6-Shogaol and Its Metabolite, 6-Paradol, in a Mouse Model of Multiple Sclerosis
por: Sapkota, Arjun, et al.
Publicado: (2019)

6-Shogaol-Rich Extract from Ginger Up-Regulates the Antioxidant Defense Systems in Cells and Mice
por: Bak, Min-Ji, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_qpv5jbl7qtf092mlbb1uu8ti02