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Chronic Alcoholism and HHV-6 Infection Synergistically Promote Neuroinflammatory Microglial Phenotypes in the Substantia Nigra of the Adult Human Brain

Both chronic alcoholism and human herpesvirus-6 (HHV-6) infection have been identified as promoters of neuroinflammation and known to cause movement-related disorders. Substantia Nigra (SN), the dopaminergic neuron-rich region of the basal ganglia, is involved in regulating motor function and the re...

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Detalles Bibliográficos
Autores principales: Jain, Nityanand, Smirnovs, Marks, Strojeva, Samanta, Murovska, Modra, Skuja, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472392/
https://www.ncbi.nlm.nih.gov/pubmed/34572401
http://dx.doi.org/10.3390/biomedicines9091216