Cargando…

Chronic Alcoholism and HHV-6 Infection Synergistically Promote Neuroinflammatory Microglial Phenotypes in the Substantia Nigra of the Adult Human Brain

Both chronic alcoholism and human herpesvirus-6 (HHV-6) infection have been identified as promoters of neuroinflammation and known to cause movement-related disorders. Substantia Nigra (SN), the dopaminergic neuron-rich region of the basal ganglia, is involved in regulating motor function and the re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jain, Nityanand, Smirnovs, Marks, Strojeva, Samanta, Murovska, Modra, Skuja, Sandra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472392/ https://www.ncbi.nlm.nih.gov/pubmed/34572401 http://dx.doi.org/10.3390/biomedicines9091216

Ejemplares similares

Alcohol-Induced Alterations in the Vascular Basement Membrane in the Substantia Nigra of the Adult Human Brain
por: Skuja, Sandra, et al.
Publicado: (2022)

Regional microglial activation in the substantia nigra is linked with fatigue in MS
por: Singhal, Tarun, et al.
Publicado: (2020)

Iron deposition in substantia nigra: abnormal iron metabolism, neuroinflammatory mechanism and clinical relevance
por: Liu, Zhuo, et al.
Publicado: (2017)

Microglial inflammation in the parkinsonian substantia nigra: relationship to alpha-synuclein deposition
por: Croisier, Emilie, et al.
Publicado: (2005)

The role of HHV-6 and HHV-7 infections in the development of fibromyalgia
por: Krumina, Angelika, et al.
Publicado: (2019)

Soemmerring and the Substantia Nigra
por: Faull, R. L. M, et al.
Publicado: (1968)

Correction: Microglial inflammation in the parkinsonian substantia nigra: relationship to alpha-synuclein deposition
por: Croisier, Emilie, et al.
Publicado: (2006)

Acute Neuroinflammatory Response in the Substantia Nigra Pars Compacta of Rats after a Local Injection of Lipopolysaccharide
por: Flores-Martinez, Yazmin M., et al.
Publicado: (2018)

Investigation of the Involvement of HHV-6 Encoded Viral Chemokine Receptors in Autoimmune Thyroiditis Development
por: Sultanova, Alina, et al.
Publicado: (2022)

HHV-6 Infection and Chemokine RANTES Signaling Pathway Disturbance in Patients with Autoimmune Thyroiditis
por: Sultanova, Alina, et al.
Publicado: (2020)

Microglial phenotypes and toll-like receptor 2 in the substantia nigra and hippocampus of incidental Lewy body disease cases and Parkinson’s disease patients
por: Doorn, Karlijn J, et al.
Publicado: (2014)

Urocortin, a CRF-like peptide, restores key indicators of damage in the substantia nigra in a neuroinflammatory model of Parkinson's disease
por: Abuirmeileh, Amjad, et al.
Publicado: (2007)

The history of the research of iron in parkinsonian substantia nigra
por: Friedman, Andrzej, et al.
Publicado: (2012)

Isolated substantia nigra involvement in brainstem demyelination
por: Mahale, Rohan R., et al.
Publicado: (2015)

Nicotine impact on rat substantia nigra compacta
por: Elgayar, Sanaa A M, et al.
Publicado: (2021)

Intranasal administration of α-synuclein preformed fibrils triggers microglial iron deposition in the substantia nigra of Macaca fascicularis
por: Guo, Jian-Jun, et al.
Publicado: (2021)

Enhanced training protects memory against amnesia produced by concurrent inactivation of amygdala and striatum, amygdala and substantia nigra, or striatum and substantia nigra
por: Salado-Castillo, Rigoberto, et al.
Publicado: (2011)

Proteome analysis of human substantia nigra in Parkinson's disease
por: Werner, Cornelius J, et al.
Publicado: (2008)

Bidirectional Modulation of Substantia Nigra Activity by Motivational State
por: Rossi, Mark A., et al.
Publicado: (2013)

Operant Self-Stimulation of Dopamine Neurons in the Substantia Nigra
por: Rossi, Mark A., et al.
Publicado: (2013)

Epstein-Barr virus encephalitis with substantia nigra involvement
por: Çelik, Tamer, et al.
Publicado: (2015)

Mesencephalic origin of the rostral Substantia nigra pars reticulata
por: Madrigal, M. Pilar, et al.
Publicado: (2015)

Glucocerebrosidase Deficiency in Substantia Nigra of Parkinson Disease Brains
por: Gegg, Matthew E, et al.
Publicado: (2012)

Degeneration of the Substantia Nigra Following Ipsilateral Striatal Infarction
por: Ohtomo, Gaku, et al.
Publicado: (2017)

Proliferation of Inhibitory Input to the Substantia Nigra in Experimental Parkinsonism
por: Faynveitz, Anna, et al.
Publicado: (2019)

Complement activation in the Parkinson's disease substantia nigra: an immunocytochemical study
por: Loeffler, David A, et al.
Publicado: (2006)

Parcellation of the human substantia nigra based on anatomical connectivity to the striatum()
por: Chowdhury, Rumana, et al.
Publicado: (2013)

Tollip, an early regulator of the acute inflammatory response in the substantia nigra
por: Humbert-Claude, Marie, et al.
Publicado: (2016)

Defective mitochondrial DNA homeostasis in the substantia nigra in Parkinson disease
por: Dölle, Christian, et al.
Publicado: (2016)

Age-Mediated Transcriptomic Changes in Adult Mouse Substantia Nigra
por: Gao, Lin, et al.
Publicado: (2013)

Sex-Related Abnormalities in Substantia Nigra Lipids in Parkinson’s Disease
por: Seyfried, T. N., et al.
Publicado: (2018)

Genetic and constitutional factors are major contributors to substantia nigra hyperechogenicity
por: Vázquez-Costa, Juan F., et al.
Publicado: (2017)

Anatomical and functional organization of the human substantia nigra and its connections
por: Zhang, Yu, et al.
Publicado: (2017)

The effect of titanium dioxide nanoparticles on mice midbrain substantia nigra
por: Heidari, Zahra, et al.
Publicado: (2019)

Oxidative stress in the aging substantia nigra and the etiology of Parkinson's disease
por: Trist, Benjamin G., et al.
Publicado: (2019)

Complementary Transcriptomic and Proteomic Analysis in the Substantia Nigra of Parkinson's Disease
por: Dong, Bao-hua, et al.
Publicado: (2021)

Angiotensin-II Modulates GABAergic Neurotransmission in the Mouse Substantia Nigra
por: Singh, Maibam R., et al.
Publicado: (2021)

Imaging of Substantia Nigra in Parkinson’s Disease: A Narrative Review
por: Feraco, Paola, et al.
Publicado: (2021)

Ferroptosis-related factors in the substantia nigra are associated with Parkinson’s disease
por: Liu, Lei, et al.
Publicado: (2023)

Activity of the Substantia Nigra Pars Reticulata during Saccade Adaptation
por: Kojima, Yoshiko, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_fv5kn26o6jedi46vlkiq8gbpqc