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Genomics in medicine: A new era in medicine

The sequencing of complete human genome revolutionized the genomic medicine. However, the complex interplay of gene-environment-lifestyle and influence of non-coding genomic regions on human health remain largely unexplored. Genomic medicine has great potential for diagnoses or disease prediction, d...

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Autores principales: Pattan, Vishwanath, Kashyap, Rahul, Bansal, Vikas, Candula, Narsimha, Koritala, Thoyaja, Surani, Salim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472545/
https://www.ncbi.nlm.nih.gov/pubmed/34631481
http://dx.doi.org/10.5662/wjm.v11.i5.231
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author Pattan, Vishwanath
Kashyap, Rahul
Bansal, Vikas
Candula, Narsimha
Koritala, Thoyaja
Surani, Salim
author_facet Pattan, Vishwanath
Kashyap, Rahul
Bansal, Vikas
Candula, Narsimha
Koritala, Thoyaja
Surani, Salim
author_sort Pattan, Vishwanath
collection PubMed
description The sequencing of complete human genome revolutionized the genomic medicine. However, the complex interplay of gene-environment-lifestyle and influence of non-coding genomic regions on human health remain largely unexplored. Genomic medicine has great potential for diagnoses or disease prediction, disease prevention and, targeted treatment. However, many of the promising tools of genomic medicine are still in their infancy and their application may be limited because of the limited knowledge we have that precludes its use in many clinical settings. In this review article, we have reviewed the evolution of genomic methodologies/tools, their limitations, and scope, for current and future clinical application.
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spelling pubmed-84725452021-10-07 Genomics in medicine: A new era in medicine Pattan, Vishwanath Kashyap, Rahul Bansal, Vikas Candula, Narsimha Koritala, Thoyaja Surani, Salim World J Methodol Frontier The sequencing of complete human genome revolutionized the genomic medicine. However, the complex interplay of gene-environment-lifestyle and influence of non-coding genomic regions on human health remain largely unexplored. Genomic medicine has great potential for diagnoses or disease prediction, disease prevention and, targeted treatment. However, many of the promising tools of genomic medicine are still in their infancy and their application may be limited because of the limited knowledge we have that precludes its use in many clinical settings. In this review article, we have reviewed the evolution of genomic methodologies/tools, their limitations, and scope, for current and future clinical application. Baishideng Publishing Group Inc 2021-09-20 /pmc/articles/PMC8472545/ /pubmed/34631481 http://dx.doi.org/10.5662/wjm.v11.i5.231 Text en ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Frontier
Pattan, Vishwanath
Kashyap, Rahul
Bansal, Vikas
Candula, Narsimha
Koritala, Thoyaja
Surani, Salim
Genomics in medicine: A new era in medicine
title Genomics in medicine: A new era in medicine
title_full Genomics in medicine: A new era in medicine
title_fullStr Genomics in medicine: A new era in medicine
title_full_unstemmed Genomics in medicine: A new era in medicine
title_short Genomics in medicine: A new era in medicine
title_sort genomics in medicine: a new era in medicine
topic Frontier
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472545/
https://www.ncbi.nlm.nih.gov/pubmed/34631481
http://dx.doi.org/10.5662/wjm.v11.i5.231
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