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Genomics in medicine: A new era in medicine
The sequencing of complete human genome revolutionized the genomic medicine. However, the complex interplay of gene-environment-lifestyle and influence of non-coding genomic regions on human health remain largely unexplored. Genomic medicine has great potential for diagnoses or disease prediction, d...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472545/ https://www.ncbi.nlm.nih.gov/pubmed/34631481 http://dx.doi.org/10.5662/wjm.v11.i5.231 |
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author | Pattan, Vishwanath Kashyap, Rahul Bansal, Vikas Candula, Narsimha Koritala, Thoyaja Surani, Salim |
author_facet | Pattan, Vishwanath Kashyap, Rahul Bansal, Vikas Candula, Narsimha Koritala, Thoyaja Surani, Salim |
author_sort | Pattan, Vishwanath |
collection | PubMed |
description | The sequencing of complete human genome revolutionized the genomic medicine. However, the complex interplay of gene-environment-lifestyle and influence of non-coding genomic regions on human health remain largely unexplored. Genomic medicine has great potential for diagnoses or disease prediction, disease prevention and, targeted treatment. However, many of the promising tools of genomic medicine are still in their infancy and their application may be limited because of the limited knowledge we have that precludes its use in many clinical settings. In this review article, we have reviewed the evolution of genomic methodologies/tools, their limitations, and scope, for current and future clinical application. |
format | Online Article Text |
id | pubmed-8472545 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-84725452021-10-07 Genomics in medicine: A new era in medicine Pattan, Vishwanath Kashyap, Rahul Bansal, Vikas Candula, Narsimha Koritala, Thoyaja Surani, Salim World J Methodol Frontier The sequencing of complete human genome revolutionized the genomic medicine. However, the complex interplay of gene-environment-lifestyle and influence of non-coding genomic regions on human health remain largely unexplored. Genomic medicine has great potential for diagnoses or disease prediction, disease prevention and, targeted treatment. However, many of the promising tools of genomic medicine are still in their infancy and their application may be limited because of the limited knowledge we have that precludes its use in many clinical settings. In this review article, we have reviewed the evolution of genomic methodologies/tools, their limitations, and scope, for current and future clinical application. Baishideng Publishing Group Inc 2021-09-20 /pmc/articles/PMC8472545/ /pubmed/34631481 http://dx.doi.org/10.5662/wjm.v11.i5.231 Text en ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
spellingShingle | Frontier Pattan, Vishwanath Kashyap, Rahul Bansal, Vikas Candula, Narsimha Koritala, Thoyaja Surani, Salim Genomics in medicine: A new era in medicine |
title | Genomics in medicine: A new era in medicine |
title_full | Genomics in medicine: A new era in medicine |
title_fullStr | Genomics in medicine: A new era in medicine |
title_full_unstemmed | Genomics in medicine: A new era in medicine |
title_short | Genomics in medicine: A new era in medicine |
title_sort | genomics in medicine: a new era in medicine |
topic | Frontier |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472545/ https://www.ncbi.nlm.nih.gov/pubmed/34631481 http://dx.doi.org/10.5662/wjm.v11.i5.231 |
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