Carbon Dioxide-Derived Biodegradable and Cationic Polycarbonates as a New siRNA Carrier for Gene Therapy in Pancreatic Cancer

Pancreatic cancer is an aggressive malignancy associated with poor prognosis and a high tendency in developing infiltration and metastasis. K-ras mutation is a major genetic disorder in pancreatic cancer patient. RNAi-based therapies can be employed for combating pancreatic cancer by silencing K-ras...

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Detalles Bibliográficos
Autores principales: Zhang, Xinmeng, Lin, Zheng-Ian, Yang, Jingyu, Liu, Guan-Lin, Hu, Zulu, Huang, Haoqiang, Li, Xiang, Liu, Qiqi, Ma, Mingze, Xu, Zhourui, Xu, Gaixia, Yong, Ken-Tye, Tsai, Wei-Chung, Tsai, Tzu-Hsien, Ko, Bao-Tsan, Chen, Chih-Kuang, Yang, Chengbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472555/
https://www.ncbi.nlm.nih.gov/pubmed/34578632
http://dx.doi.org/10.3390/nano11092312

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