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Female Mice Reaching Exceptionally High Old Age Have Preserved 20S Proteasome Activities

Oxidized, damaged and misfolded proteins accumulate during aging and contribute to impaired cell function and tissue homeodynamics. Damaged proteins are degraded by cellular clearance mechanisms like the 20S proteasome. Aging relates to low 20S proteasome function, whereas long-lived species show hi...

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Detalles Bibliográficos
Autores principales:	Martínez de Toda, Irene, Rattan, Suresh I. S., De la Fuente, Mónica, Arranz, Lorena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472714/ https://www.ncbi.nlm.nih.gov/pubmed/34573029 http://dx.doi.org/10.3390/antiox10091397

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