Inclusion of Medium-Chain Triglyceride in Lipid-Based Formulation of Cannabidiol Facilitates Micellar Solubilization In Vitro, but In Vivo Performance Remains Superior with Pure Sesame Oil Vehicle

Oral sesame oil-based formulation facilitates the delivery of poorly water-soluble drug cannabidiol (CBD) to the lymphatic system and blood circulation. However, this natural oil-based formulation also leads to considerable variability in absorption of CBD. In this work, the performance of lipid-bas...

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Detalles Bibliográficos
Autores principales: Feng, Wanshan, Qin, Chaolong, Cipolla, Elena, Lee, Jong Bong, Zgair, Atheer, Chu, Yenju, Ortori, Catherine A., Stocks, Michael J., Constantinescu, Cris S., Barrett, David A., Fischer, Peter M., Gershkovich, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472830/
https://www.ncbi.nlm.nih.gov/pubmed/34575426
http://dx.doi.org/10.3390/pharmaceutics13091349

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