A Novel Class of Norovirus Inhibitors Targeting the Viral Protease with Potent Antiviral Activity In Vitro and In Vivo

Human noroviruses (HuNoVs) are the most common cause of viral gastroenteritis resulting annually in ~219,000 deaths and a societal cost of ~USD 60 billion, and no antivirals or vaccines are available. Here, we assess the anti-norovirus activity of new peptidomimetic aldehydes related to the protease...

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Detalles Bibliográficos
Autores principales: Van Dycke, Jana, Dai, Wenhao, Stylianidou, Zoe, Li, Jian, Cuvry, Arno, Roux, Emma, Li, Bingqian, Rymenants, Jasper, Bervoets, Lindsey, de Witte, Peter, Liu, Hong, Neyts, Johan, Rocha-Pereira, Joana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472913/
https://www.ncbi.nlm.nih.gov/pubmed/34578432
http://dx.doi.org/10.3390/v13091852

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