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One Health Investigation of SARS-CoV-2 Infection and Seropositivity among Pets in Households with Confirmed Human COVID-19 Cases—Utah and Wisconsin, 2020
Approximately 67% of U.S. households have pets. Limited data are available on SARS-CoV-2 in pets. We assessed SARS-CoV-2 infection in pets during a COVID-19 household transmission investigation. Pets from households with ≥1 person with laboratory-confirmed COVID-19 were eligible for inclusion from A...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472995/ https://www.ncbi.nlm.nih.gov/pubmed/34578394 http://dx.doi.org/10.3390/v13091813 |
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author | Goryoka, Grace W. Cossaboom, Caitlin M. Gharpure, Radhika Dawson, Patrick Tansey, Cassandra Rossow, John Mrotz, Victoria Rooney, Jane Torchetti, Mia Loiacono, Christina M. Killian, Mary L. Jenkins-Moore, Melinda Lim, Ailam Poulsen, Keith Christensen, Dan Sweet, Emma Peterson, Dallin Sangster, Anna L. Young, Erin L. Oakeson, Kelly F. Taylor, Dean Price, Amanda Kiphibane, Tair Klos, Rachel Konkle, Darlene Bhattacharyya, Sanjib Dasu, Trivikram Chu, Victoria T. Lewis, Nathaniel M. Queen, Krista Zhang, Jing Uehara, Anna Dietrich, Elizabeth A. Tong, Suxiang Kirking, Hannah L. Doty, Jeffrey B. Murrell, Laura S. Spengler, Jessica R. Straily, Anne Wallace, Ryan Barton Behravesh, Casey |
author_facet | Goryoka, Grace W. Cossaboom, Caitlin M. Gharpure, Radhika Dawson, Patrick Tansey, Cassandra Rossow, John Mrotz, Victoria Rooney, Jane Torchetti, Mia Loiacono, Christina M. Killian, Mary L. Jenkins-Moore, Melinda Lim, Ailam Poulsen, Keith Christensen, Dan Sweet, Emma Peterson, Dallin Sangster, Anna L. Young, Erin L. Oakeson, Kelly F. Taylor, Dean Price, Amanda Kiphibane, Tair Klos, Rachel Konkle, Darlene Bhattacharyya, Sanjib Dasu, Trivikram Chu, Victoria T. Lewis, Nathaniel M. Queen, Krista Zhang, Jing Uehara, Anna Dietrich, Elizabeth A. Tong, Suxiang Kirking, Hannah L. Doty, Jeffrey B. Murrell, Laura S. Spengler, Jessica R. Straily, Anne Wallace, Ryan Barton Behravesh, Casey |
author_sort | Goryoka, Grace W. |
collection | PubMed |
description | Approximately 67% of U.S. households have pets. Limited data are available on SARS-CoV-2 in pets. We assessed SARS-CoV-2 infection in pets during a COVID-19 household transmission investigation. Pets from households with ≥1 person with laboratory-confirmed COVID-19 were eligible for inclusion from April–May 2020. We enrolled 37 dogs and 19 cats from 34 households. All oropharyngeal, nasal, and rectal swabs tested negative by rRT-PCR; one dog’s fur swabs (2%) tested positive by rRT-PCR at the first sampling. Among 47 pets with serological results, eight (17%) pets (four dogs, four cats) from 6/30 (20%) households had detectable SARS-CoV-2 neutralizing antibodies. In households with a seropositive pet, the proportion of people with laboratory-confirmed COVID-19 was greater (median 79%; range: 40–100%) compared to households with no seropositive pet (median 37%; range: 13–100%) (p = 0.01). Thirty-three pets with serologic results had frequent daily contact (≥1 h) with the index patient before the person’s COVID-19 diagnosis. Of these 33 pets, 14 (42%) had decreased contact with the index patient after diagnosis and none were seropositive; of the 19 (58%) pets with continued contact, four (21%) were seropositive. Seropositive pets likely acquired infection after contact with people with COVID-19. People with COVID-19 should restrict contact with pets and other animals. |
format | Online Article Text |
id | pubmed-8472995 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-84729952021-09-28 One Health Investigation of SARS-CoV-2 Infection and Seropositivity among Pets in Households with Confirmed Human COVID-19 Cases—Utah and Wisconsin, 2020 Goryoka, Grace W. Cossaboom, Caitlin M. Gharpure, Radhika Dawson, Patrick Tansey, Cassandra Rossow, John Mrotz, Victoria Rooney, Jane Torchetti, Mia Loiacono, Christina M. Killian, Mary L. Jenkins-Moore, Melinda Lim, Ailam Poulsen, Keith Christensen, Dan Sweet, Emma Peterson, Dallin Sangster, Anna L. Young, Erin L. Oakeson, Kelly F. Taylor, Dean Price, Amanda Kiphibane, Tair Klos, Rachel Konkle, Darlene Bhattacharyya, Sanjib Dasu, Trivikram Chu, Victoria T. Lewis, Nathaniel M. Queen, Krista Zhang, Jing Uehara, Anna Dietrich, Elizabeth A. Tong, Suxiang Kirking, Hannah L. Doty, Jeffrey B. Murrell, Laura S. Spengler, Jessica R. Straily, Anne Wallace, Ryan Barton Behravesh, Casey Viruses Article Approximately 67% of U.S. households have pets. Limited data are available on SARS-CoV-2 in pets. We assessed SARS-CoV-2 infection in pets during a COVID-19 household transmission investigation. Pets from households with ≥1 person with laboratory-confirmed COVID-19 were eligible for inclusion from April–May 2020. We enrolled 37 dogs and 19 cats from 34 households. All oropharyngeal, nasal, and rectal swabs tested negative by rRT-PCR; one dog’s fur swabs (2%) tested positive by rRT-PCR at the first sampling. Among 47 pets with serological results, eight (17%) pets (four dogs, four cats) from 6/30 (20%) households had detectable SARS-CoV-2 neutralizing antibodies. In households with a seropositive pet, the proportion of people with laboratory-confirmed COVID-19 was greater (median 79%; range: 40–100%) compared to households with no seropositive pet (median 37%; range: 13–100%) (p = 0.01). Thirty-three pets with serologic results had frequent daily contact (≥1 h) with the index patient before the person’s COVID-19 diagnosis. Of these 33 pets, 14 (42%) had decreased contact with the index patient after diagnosis and none were seropositive; of the 19 (58%) pets with continued contact, four (21%) were seropositive. Seropositive pets likely acquired infection after contact with people with COVID-19. People with COVID-19 should restrict contact with pets and other animals. MDPI 2021-09-12 /pmc/articles/PMC8472995/ /pubmed/34578394 http://dx.doi.org/10.3390/v13091813 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Goryoka, Grace W. Cossaboom, Caitlin M. Gharpure, Radhika Dawson, Patrick Tansey, Cassandra Rossow, John Mrotz, Victoria Rooney, Jane Torchetti, Mia Loiacono, Christina M. Killian, Mary L. Jenkins-Moore, Melinda Lim, Ailam Poulsen, Keith Christensen, Dan Sweet, Emma Peterson, Dallin Sangster, Anna L. Young, Erin L. Oakeson, Kelly F. Taylor, Dean Price, Amanda Kiphibane, Tair Klos, Rachel Konkle, Darlene Bhattacharyya, Sanjib Dasu, Trivikram Chu, Victoria T. Lewis, Nathaniel M. Queen, Krista Zhang, Jing Uehara, Anna Dietrich, Elizabeth A. Tong, Suxiang Kirking, Hannah L. Doty, Jeffrey B. Murrell, Laura S. Spengler, Jessica R. Straily, Anne Wallace, Ryan Barton Behravesh, Casey One Health Investigation of SARS-CoV-2 Infection and Seropositivity among Pets in Households with Confirmed Human COVID-19 Cases—Utah and Wisconsin, 2020 |
title | One Health Investigation of SARS-CoV-2 Infection and Seropositivity among Pets in Households with Confirmed Human COVID-19 Cases—Utah and Wisconsin, 2020 |
title_full | One Health Investigation of SARS-CoV-2 Infection and Seropositivity among Pets in Households with Confirmed Human COVID-19 Cases—Utah and Wisconsin, 2020 |
title_fullStr | One Health Investigation of SARS-CoV-2 Infection and Seropositivity among Pets in Households with Confirmed Human COVID-19 Cases—Utah and Wisconsin, 2020 |
title_full_unstemmed | One Health Investigation of SARS-CoV-2 Infection and Seropositivity among Pets in Households with Confirmed Human COVID-19 Cases—Utah and Wisconsin, 2020 |
title_short | One Health Investigation of SARS-CoV-2 Infection and Seropositivity among Pets in Households with Confirmed Human COVID-19 Cases—Utah and Wisconsin, 2020 |
title_sort | one health investigation of sars-cov-2 infection and seropositivity among pets in households with confirmed human covid-19 cases—utah and wisconsin, 2020 |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472995/ https://www.ncbi.nlm.nih.gov/pubmed/34578394 http://dx.doi.org/10.3390/v13091813 |
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