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One Health Investigation of SARS-CoV-2 Infection and Seropositivity among Pets in Households with Confirmed Human COVID-19 Cases—Utah and Wisconsin, 2020

Approximately 67% of U.S. households have pets. Limited data are available on SARS-CoV-2 in pets. We assessed SARS-CoV-2 infection in pets during a COVID-19 household transmission investigation. Pets from households with ≥1 person with laboratory-confirmed COVID-19 were eligible for inclusion from A...

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Autores principales: Goryoka, Grace W., Cossaboom, Caitlin M., Gharpure, Radhika, Dawson, Patrick, Tansey, Cassandra, Rossow, John, Mrotz, Victoria, Rooney, Jane, Torchetti, Mia, Loiacono, Christina M., Killian, Mary L., Jenkins-Moore, Melinda, Lim, Ailam, Poulsen, Keith, Christensen, Dan, Sweet, Emma, Peterson, Dallin, Sangster, Anna L., Young, Erin L., Oakeson, Kelly F., Taylor, Dean, Price, Amanda, Kiphibane, Tair, Klos, Rachel, Konkle, Darlene, Bhattacharyya, Sanjib, Dasu, Trivikram, Chu, Victoria T., Lewis, Nathaniel M., Queen, Krista, Zhang, Jing, Uehara, Anna, Dietrich, Elizabeth A., Tong, Suxiang, Kirking, Hannah L., Doty, Jeffrey B., Murrell, Laura S., Spengler, Jessica R., Straily, Anne, Wallace, Ryan, Barton Behravesh, Casey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472995/
https://www.ncbi.nlm.nih.gov/pubmed/34578394
http://dx.doi.org/10.3390/v13091813
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author Goryoka, Grace W.
Cossaboom, Caitlin M.
Gharpure, Radhika
Dawson, Patrick
Tansey, Cassandra
Rossow, John
Mrotz, Victoria
Rooney, Jane
Torchetti, Mia
Loiacono, Christina M.
Killian, Mary L.
Jenkins-Moore, Melinda
Lim, Ailam
Poulsen, Keith
Christensen, Dan
Sweet, Emma
Peterson, Dallin
Sangster, Anna L.
Young, Erin L.
Oakeson, Kelly F.
Taylor, Dean
Price, Amanda
Kiphibane, Tair
Klos, Rachel
Konkle, Darlene
Bhattacharyya, Sanjib
Dasu, Trivikram
Chu, Victoria T.
Lewis, Nathaniel M.
Queen, Krista
Zhang, Jing
Uehara, Anna
Dietrich, Elizabeth A.
Tong, Suxiang
Kirking, Hannah L.
Doty, Jeffrey B.
Murrell, Laura S.
Spengler, Jessica R.
Straily, Anne
Wallace, Ryan
Barton Behravesh, Casey
author_facet Goryoka, Grace W.
Cossaboom, Caitlin M.
Gharpure, Radhika
Dawson, Patrick
Tansey, Cassandra
Rossow, John
Mrotz, Victoria
Rooney, Jane
Torchetti, Mia
Loiacono, Christina M.
Killian, Mary L.
Jenkins-Moore, Melinda
Lim, Ailam
Poulsen, Keith
Christensen, Dan
Sweet, Emma
Peterson, Dallin
Sangster, Anna L.
Young, Erin L.
Oakeson, Kelly F.
Taylor, Dean
Price, Amanda
Kiphibane, Tair
Klos, Rachel
Konkle, Darlene
Bhattacharyya, Sanjib
Dasu, Trivikram
Chu, Victoria T.
Lewis, Nathaniel M.
Queen, Krista
Zhang, Jing
Uehara, Anna
Dietrich, Elizabeth A.
Tong, Suxiang
Kirking, Hannah L.
Doty, Jeffrey B.
Murrell, Laura S.
Spengler, Jessica R.
Straily, Anne
Wallace, Ryan
Barton Behravesh, Casey
author_sort Goryoka, Grace W.
collection PubMed
description Approximately 67% of U.S. households have pets. Limited data are available on SARS-CoV-2 in pets. We assessed SARS-CoV-2 infection in pets during a COVID-19 household transmission investigation. Pets from households with ≥1 person with laboratory-confirmed COVID-19 were eligible for inclusion from April–May 2020. We enrolled 37 dogs and 19 cats from 34 households. All oropharyngeal, nasal, and rectal swabs tested negative by rRT-PCR; one dog’s fur swabs (2%) tested positive by rRT-PCR at the first sampling. Among 47 pets with serological results, eight (17%) pets (four dogs, four cats) from 6/30 (20%) households had detectable SARS-CoV-2 neutralizing antibodies. In households with a seropositive pet, the proportion of people with laboratory-confirmed COVID-19 was greater (median 79%; range: 40–100%) compared to households with no seropositive pet (median 37%; range: 13–100%) (p = 0.01). Thirty-three pets with serologic results had frequent daily contact (≥1 h) with the index patient before the person’s COVID-19 diagnosis. Of these 33 pets, 14 (42%) had decreased contact with the index patient after diagnosis and none were seropositive; of the 19 (58%) pets with continued contact, four (21%) were seropositive. Seropositive pets likely acquired infection after contact with people with COVID-19. People with COVID-19 should restrict contact with pets and other animals.
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spelling pubmed-84729952021-09-28 One Health Investigation of SARS-CoV-2 Infection and Seropositivity among Pets in Households with Confirmed Human COVID-19 Cases—Utah and Wisconsin, 2020 Goryoka, Grace W. Cossaboom, Caitlin M. Gharpure, Radhika Dawson, Patrick Tansey, Cassandra Rossow, John Mrotz, Victoria Rooney, Jane Torchetti, Mia Loiacono, Christina M. Killian, Mary L. Jenkins-Moore, Melinda Lim, Ailam Poulsen, Keith Christensen, Dan Sweet, Emma Peterson, Dallin Sangster, Anna L. Young, Erin L. Oakeson, Kelly F. Taylor, Dean Price, Amanda Kiphibane, Tair Klos, Rachel Konkle, Darlene Bhattacharyya, Sanjib Dasu, Trivikram Chu, Victoria T. Lewis, Nathaniel M. Queen, Krista Zhang, Jing Uehara, Anna Dietrich, Elizabeth A. Tong, Suxiang Kirking, Hannah L. Doty, Jeffrey B. Murrell, Laura S. Spengler, Jessica R. Straily, Anne Wallace, Ryan Barton Behravesh, Casey Viruses Article Approximately 67% of U.S. households have pets. Limited data are available on SARS-CoV-2 in pets. We assessed SARS-CoV-2 infection in pets during a COVID-19 household transmission investigation. Pets from households with ≥1 person with laboratory-confirmed COVID-19 were eligible for inclusion from April–May 2020. We enrolled 37 dogs and 19 cats from 34 households. All oropharyngeal, nasal, and rectal swabs tested negative by rRT-PCR; one dog’s fur swabs (2%) tested positive by rRT-PCR at the first sampling. Among 47 pets with serological results, eight (17%) pets (four dogs, four cats) from 6/30 (20%) households had detectable SARS-CoV-2 neutralizing antibodies. In households with a seropositive pet, the proportion of people with laboratory-confirmed COVID-19 was greater (median 79%; range: 40–100%) compared to households with no seropositive pet (median 37%; range: 13–100%) (p = 0.01). Thirty-three pets with serologic results had frequent daily contact (≥1 h) with the index patient before the person’s COVID-19 diagnosis. Of these 33 pets, 14 (42%) had decreased contact with the index patient after diagnosis and none were seropositive; of the 19 (58%) pets with continued contact, four (21%) were seropositive. Seropositive pets likely acquired infection after contact with people with COVID-19. People with COVID-19 should restrict contact with pets and other animals. MDPI 2021-09-12 /pmc/articles/PMC8472995/ /pubmed/34578394 http://dx.doi.org/10.3390/v13091813 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Goryoka, Grace W.
Cossaboom, Caitlin M.
Gharpure, Radhika
Dawson, Patrick
Tansey, Cassandra
Rossow, John
Mrotz, Victoria
Rooney, Jane
Torchetti, Mia
Loiacono, Christina M.
Killian, Mary L.
Jenkins-Moore, Melinda
Lim, Ailam
Poulsen, Keith
Christensen, Dan
Sweet, Emma
Peterson, Dallin
Sangster, Anna L.
Young, Erin L.
Oakeson, Kelly F.
Taylor, Dean
Price, Amanda
Kiphibane, Tair
Klos, Rachel
Konkle, Darlene
Bhattacharyya, Sanjib
Dasu, Trivikram
Chu, Victoria T.
Lewis, Nathaniel M.
Queen, Krista
Zhang, Jing
Uehara, Anna
Dietrich, Elizabeth A.
Tong, Suxiang
Kirking, Hannah L.
Doty, Jeffrey B.
Murrell, Laura S.
Spengler, Jessica R.
Straily, Anne
Wallace, Ryan
Barton Behravesh, Casey
One Health Investigation of SARS-CoV-2 Infection and Seropositivity among Pets in Households with Confirmed Human COVID-19 Cases—Utah and Wisconsin, 2020
title One Health Investigation of SARS-CoV-2 Infection and Seropositivity among Pets in Households with Confirmed Human COVID-19 Cases—Utah and Wisconsin, 2020
title_full One Health Investigation of SARS-CoV-2 Infection and Seropositivity among Pets in Households with Confirmed Human COVID-19 Cases—Utah and Wisconsin, 2020
title_fullStr One Health Investigation of SARS-CoV-2 Infection and Seropositivity among Pets in Households with Confirmed Human COVID-19 Cases—Utah and Wisconsin, 2020
title_full_unstemmed One Health Investigation of SARS-CoV-2 Infection and Seropositivity among Pets in Households with Confirmed Human COVID-19 Cases—Utah and Wisconsin, 2020
title_short One Health Investigation of SARS-CoV-2 Infection and Seropositivity among Pets in Households with Confirmed Human COVID-19 Cases—Utah and Wisconsin, 2020
title_sort one health investigation of sars-cov-2 infection and seropositivity among pets in households with confirmed human covid-19 cases—utah and wisconsin, 2020
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472995/
https://www.ncbi.nlm.nih.gov/pubmed/34578394
http://dx.doi.org/10.3390/v13091813
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