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Structure-Guided Creation of an Anti-HA Stalk Antibody F11 Derivative That Neutralizes Both F11-Sensitive and -Resistant Influenza A(H1N1)pdm09 Viruses
The stalk domain of influenza virus envelope glycoprotein hemagglutinin (HA) constitutes the axis connecting the head and transmembrane domains, and plays pivotal roles in conformational rearrangements of HA for virus infection. Here we characterized molecular interactions between the anti-HA stalk...
Autores principales: | Kotani, Osamu, Suzuki, Yasushi, Saito, Shinji, Ainai, Akira, Ueno, Akira, Hemmi, Takuya, Sano, Kaori, Tabata, Koshiro, Yokoyama, Masaru, Suzuki, Tadaki, Hasegawa, Hideki, Sato, Hironori |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473006/ https://www.ncbi.nlm.nih.gov/pubmed/34578314 http://dx.doi.org/10.3390/v13091733 |
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