CP100356 Hydrochloride, a P-Glycoprotein Inhibitor, Inhibits Lassa Virus Entry: Implication of a Candidate Pan-Mammarenavirus Entry Inhibitor

Lassa virus (LASV)—a member of the family Arenaviridae—causes Lassa fever in humans and is endemic in West Africa. Currently, no approved drugs are available. We screened 2480 small compounds for their potential antiviral activity using pseudotyped vesicular stomatitis virus harboring the LASV glyco...

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Detalles Bibliográficos
Autores principales: Takenaga, Toru, Zhang, Zihan, Muramoto, Yukiko, Fehling, Sarah Katharina, Hirabayashi, Ai, Takamatsu, Yuki, Kajikawa, Junichi, Miyamoto, Sho, Nakano, Masahiro, Urata, Shuzo, Groseth, Allison, Strecker, Thomas, Noda, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473031/
https://www.ncbi.nlm.nih.gov/pubmed/34578344
http://dx.doi.org/10.3390/v13091763

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