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The MAPK/ERK Pathway and the Role of DUSP1 in JCPyV Infection of Primary Astrocytes

JC polyomavirus (JCPyV) is a neuroinvasive pathogen causing a fatal, demyelinating disease of the central nervous system (CNS) known as progressive multifocal leukoencephalopathy (PML). Within the CNS, JCPyV predominately targets two cell types: oligodendrocytes and astrocytes. The underlying mechan...

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Detalles Bibliográficos
Autores principales:	Wilczek, Michael P., Armstrong, Francesca J., Geohegan, Remi P., Mayberry, Colleen L., DuShane, Jeanne K., King, Benjamin L., Maginnis, Melissa S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473072/ https://www.ncbi.nlm.nih.gov/pubmed/34578413 http://dx.doi.org/10.3390/v13091834

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