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Protease, Growth Factor, and Heparanase-Mediated Syndecan-1 Shedding Leads to Enhanced HSV-1 Egress

Heparan sulfate (HS) and heparan sulfate proteoglycans (HSPGs) are considered important for the entry of many different viruses. Previously, we demonstrated that heparanase (HPSE), the host enzyme responsible for cleaving HS chains, is upregulated by herpes simplex virus-1 (HSV-1) infection. Higher...

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Detalles Bibliográficos
Autores principales: Karasneh, Ghadah A., Kapoor, Divya, Bellamkonda, Navya, Patil, Chandrashekhar D., Shukla, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473078/
https://www.ncbi.nlm.nih.gov/pubmed/34578329
http://dx.doi.org/10.3390/v13091748