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A Structural Perspective of the Role of IP6 in Immature and Mature Retroviral Assembly

The small cellular molecule inositol hexakisphosphate (IP6) has been known for ~20 years to promote the in vitro assembly of HIV-1 into immature virus-like particles. However, the molecular details underlying this effect have been determined only recently, with the identification of the IP6 binding...

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Detalles Bibliográficos
Autores principales: Obr, Martin, Schur, Florian K. M., Dick, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473085/
https://www.ncbi.nlm.nih.gov/pubmed/34578434
http://dx.doi.org/10.3390/v13091853