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A Case of Rubella Caused by Rubella Vaccination
We present an extremely rare case of rubella that developed after rubella vaccine administration. A 54-year-old man complained of back and neck pain for some days. He presented with generalized rash and arthralgia that had persisted for two days before his visit. His vital signs were normal, and art...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473103/ https://www.ncbi.nlm.nih.gov/pubmed/34579277 http://dx.doi.org/10.3390/vaccines9091040 |
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author | Kamada, Momoka Kenzaka, Tsuneaki |
author_facet | Kamada, Momoka Kenzaka, Tsuneaki |
author_sort | Kamada, Momoka |
collection | PubMed |
description | We present an extremely rare case of rubella that developed after rubella vaccine administration. A 54-year-old man complained of back and neck pain for some days. He presented with generalized rash and arthralgia that had persisted for two days before his visit. His vital signs were normal, and arthralgia had disappeared during an examination, but lymphadenopathy in the left posterior neck and pink papules were observed throughout the body. He had received his first Rubella vaccination 17 days before this visit and had attended a crowded festival. Owing to the rubella epidemic in that prefecture, we performed a rubella antibody test and polymerase chain reaction assay using blood, urine, and pharyngeal swab specimens. Rubella IgG and IgM antibody titers were 3 and 1.48, respectively. The pharyngeal swab yielded positive results for the 1a vaccine strain. Therefore, he was diagnosed with rubella due to rubella vaccination. His symptoms improved eventually. His clinical course was uncomplicated. Symptoms resolved within one week without specific treatment. The vaccine rubella strain is not as highly infectious as wild-type rubella strains. If rubella symptoms appear after vaccination, it must be investigated whether these are vaccine-specific adverse reactions, wild-strain rubella onset, or other eruptive viral infections. |
format | Online Article Text |
id | pubmed-8473103 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-84731032021-09-28 A Case of Rubella Caused by Rubella Vaccination Kamada, Momoka Kenzaka, Tsuneaki Vaccines (Basel) Case Report We present an extremely rare case of rubella that developed after rubella vaccine administration. A 54-year-old man complained of back and neck pain for some days. He presented with generalized rash and arthralgia that had persisted for two days before his visit. His vital signs were normal, and arthralgia had disappeared during an examination, but lymphadenopathy in the left posterior neck and pink papules were observed throughout the body. He had received his first Rubella vaccination 17 days before this visit and had attended a crowded festival. Owing to the rubella epidemic in that prefecture, we performed a rubella antibody test and polymerase chain reaction assay using blood, urine, and pharyngeal swab specimens. Rubella IgG and IgM antibody titers were 3 and 1.48, respectively. The pharyngeal swab yielded positive results for the 1a vaccine strain. Therefore, he was diagnosed with rubella due to rubella vaccination. His symptoms improved eventually. His clinical course was uncomplicated. Symptoms resolved within one week without specific treatment. The vaccine rubella strain is not as highly infectious as wild-type rubella strains. If rubella symptoms appear after vaccination, it must be investigated whether these are vaccine-specific adverse reactions, wild-strain rubella onset, or other eruptive viral infections. MDPI 2021-09-18 /pmc/articles/PMC8473103/ /pubmed/34579277 http://dx.doi.org/10.3390/vaccines9091040 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Kamada, Momoka Kenzaka, Tsuneaki A Case of Rubella Caused by Rubella Vaccination |
title | A Case of Rubella Caused by Rubella Vaccination |
title_full | A Case of Rubella Caused by Rubella Vaccination |
title_fullStr | A Case of Rubella Caused by Rubella Vaccination |
title_full_unstemmed | A Case of Rubella Caused by Rubella Vaccination |
title_short | A Case of Rubella Caused by Rubella Vaccination |
title_sort | case of rubella caused by rubella vaccination |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473103/ https://www.ncbi.nlm.nih.gov/pubmed/34579277 http://dx.doi.org/10.3390/vaccines9091040 |
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