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Genotype of Immunologically Hot or Cold Tumors Determines the Antitumor Immune Response and Efficacy by Fully Virulent Retargeted oHSV

We report on the efficacy of the non-attenuated HER2-retargeted oHSV named R-337 against the immunologically hot CT26-HER2 tumor, and an insight into the basis of the immune protection. Preliminarily, we conducted an RNA immune profiling and immune cell content characterization of CT26-HER2 tumor in...

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Detalles Bibliográficos
Autores principales: Gianni, Tatiana, Leoni, Valerio, Sanapo, Mara, Parenti, Federico, Bressanin, Daniela, Barboni, Catia, Zaghini, Anna, Campadelli-Fiume, Gabriella, Vannini, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473155/
https://www.ncbi.nlm.nih.gov/pubmed/34578328
http://dx.doi.org/10.3390/v13091747

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