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Genotype of Immunologically Hot or Cold Tumors Determines the Antitumor Immune Response and Efficacy by Fully Virulent Retargeted oHSV
We report on the efficacy of the non-attenuated HER2-retargeted oHSV named R-337 against the immunologically hot CT26-HER2 tumor, and an insight into the basis of the immune protection. Preliminarily, we conducted an RNA immune profiling and immune cell content characterization of CT26-HER2 tumor in...
Autores principales: | Gianni, Tatiana, Leoni, Valerio, Sanapo, Mara, Parenti, Federico, Bressanin, Daniela, Barboni, Catia, Zaghini, Anna, Campadelli-Fiume, Gabriella, Vannini, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473155/ https://www.ncbi.nlm.nih.gov/pubmed/34578328 http://dx.doi.org/10.3390/v13091747 |
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