Modification Strategy of D-leucine Residue Addition on a Novel Peptide from Odorrana schmackeri, with Enhanced Bioactivity and In Vivo Efficacy

Brevinins are a well-characterised, frog-skin-derived, antimicrobial peptide (AMP) family, but their applications are limited by high cytotoxicity. In this study, a wild-type des-Leu2 brevinin peptide, named brevinin-1OS (B1OS), was identified from Odorrana schmackeri. To explore the significant rol...

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Detalles Bibliográficos
Autores principales: Yao, Aifang, Ma, Yingxue, Chen, Xiaoling, Zhou, Mei, Xi, Xinping, Ma, Chengbang, Ren, Shen, Chen, Tianbao, Shaw, Chris, Wang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473181/
https://www.ncbi.nlm.nih.gov/pubmed/34564615
http://dx.doi.org/10.3390/toxins13090611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473181/
https://www.ncbi.nlm.nih.gov/pubmed/34564615
http://dx.doi.org/10.3390/toxins13090611

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